What antiepileptic drugs cause elevation of liver transaminases?
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What antiepileptic drugs cause elevation of liver transaminases? Bottom line: Older antiepileptic medications that induce liver enzyme pathways may be associated with elevated transaminases, but rarely cause hepatotoxicity (SOR: B, based on cohort studies). Elevation of liver transaminases is unlikely with most new antiepileptic agents (SOR: C, disease-oriented outcomes).
Evidence Based Practice 17(02): 14