dc.contributor.author | White, Sarah | eng |
dc.contributor.author | Mounsey, Anne | eng |
dc.contributor.author | Tillett, Janine S. | eng |
dc.date.issued | 2014 | eng |
dc.description.abstract | Q. Which prophylactic therapies best prevent gout attacks? A. Allopurinol and febuxostat reduce the frequency of gout attacks equally after 8 weeks of treatment (strength of recommendation [SOR]: B, multiple randomized control trials [RCTs] with limitations). Intravenous pegloticase decreases serum uric acid and gout attacks and improves quality of life (QOL) (SOR: A, 2 RCTs). Colchicine reduces gout attacks when combined with probenecid or allopurinol at the start of urate-lowering therapy (SOR: B, 1 high-quality and 1 low-quality RCT). | eng |
dc.identifier.uri | http://hdl.handle.net/10355/41921 | eng |
dc.language | English | eng |
dc.publisher | Family Physicians Inquiries Network | eng |
dc.relation.ispartofcollection | Clinical Inquiries, 2014 (MU) | eng |
dc.relation.ispartofcommunity | University of Missouri-Columbia. School of Medicine. Department of Family and Community Medicine. Family Physicians Inquiries Network. | eng |
dc.relation.ispartofseries | Journal of family practice, 63, no. 04 (April 2014): 216,221 | eng |
dc.rights | OpenAccess. | eng |
dc.rights.license | This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 3.0 License. | eng |
dc.title | Which prophylactic therapies best prevent gout attacks? | eng |
dc.type | Article | eng |