Browsing 2009 MU dissertations - Freely available online by Thesis Department "Biochemistry (MU)"
Now showing items 1-3 of 3
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Glomerulosclerosis in the Col1a2-deficient mouse model : homotrimer pathogenesis and MMP expression
(University of Missouri--Columbia, 2009)The Col1a2-deficient (oim) mouse model exclusively synthesizes homotrimeric type I collagen due to the lack of functional pro [alpha] 2(I) collagen chains. The mouse develops a type I collagen glomerulopathy that has ... -
Secretory phospholipase A2-IIA in Alzheimer's disease and inflammatory responses in astrocytes
(University of Missouri--Columbia, 2009)Alzheimer's disease (AD) is a progressive, fatal neurodegenerative disease marked with dementia. Secretory phospholipase A2-IIA (sPLA2-IIA) is an inflammatory protein known to have a role in the pathogenesis of multiple ... -
Targeting estrogen- and hedgehog-signaling pathways in prostate cancer
(University of Missouri--Columbia, 2009)Prostate cancer is the second most frequent cause of cancer deaths in men, and the risk to develop cancer increases with age. Since the lifespan of the society is progressively increasing, the importance of preventing the ...