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Recent Submissions

  • Thiazolidinedione Therapy for Managing Metabolic Syndrome 

    Geurin, Michael D.; St. Anna, Leilani (Family Physicians Inquiries Network, 2010-12)
    There is no patient-oriented evidence supporting the use of TZD therapy in patients in the general population who have metabolic syndrome. Rosiglitazone (Avandia) use decreases cardiovascular morbidity and mortality in ...
  • Sunscreen Use for Skin Cancer Prevention 

    Bouknight, Patricia; Bowling, Andrew; Kovach, Fran E. (Family Physicians Inquiries Network, 2010-10)
    Daily sunscreen use reduces the incidence of squamous cell carcinoma but not the incidence of basal cell carcinoma. (Strength of Recommendation [SOR]: B, based on a single randomized controlled trial with less than 13 years ...
  • Management of Alcohol Withdrawal Syndrome 

    Ricks, Janet; Replogle, William H.; Cook, Nakia Joyce (Family Physicians Inquiries Network, 2010-08)
    AWS may be managed with outpatient therapy if the patient has mild to moderate symptoms. (Strength of Recommendation [SOR]: B, based on one randomized, prospective trial). The Clinical Institute Withdrawal Assessment Scale ...
  • Combination Therapy for Postmenopausal Osteoporosis 

    Tagliarino, Heather; Howard, Ellen (Family Physicians Inquiries Network, 2010-02)
    There is insufficient evidence to recommend combination therapy for the routine management of postmenopausal osteoporosis. (Strength of Recommendation [SOR]: C, based on expert opinion). Combination therapy with parathyroid ...
  • When should you treat tongue-tie in a newborn? 

    Cho, Anthony; Kelsberg, Gary; Safranek, Sarah (Family Physicians Inquiries Network, 2010-12)
    Consider treatment when the infant is having difficulty breastfeeding. Infants with mild to moderate tongue-tie, or ankyloglossia, are likely to breastfeed successfully and usually require no treatment (strength of ...
  • How does electronic fetal heart rate monitoring affect labor and delivery outcomes? 

    Barstow, Craig; Gauer, Robert; Jamieson, Barbara (Family Physicians Inquiries Network, 2010-11)
    Continuous electronic fetal monitoring (EFM) reduces the risk of neonatal seizure by 50% compared with intermittent auscultation (IA) (strength of recommendation [SOR]: A, systematic review of randomized controlled trials ...
  • Which patients benefit from lowering LDL to <100 mg/dL? 

    Evensen, Ann E.; Elliott, Marguerite; Hooper-Lane, Christopher (Family Physicians Inquiries Network, 2010-12)
    Patients who have coronary heart disease (CHD) or are at high risk for CHD should aim for a low-density lipoprotein (LDL) target of <100 mg/dL. An LDL target of <70 mg/dL is an option for very-high-risk patients (strength ...
  • How should we monitor men receiving testosterone replacement therapy? 

    Alsina, Manuel; St. Anna, Leilani (Family Physicians Inquiries Network, 2010-12)
    Monitor hematocrit and bone mineral density (BMD) (strength of recommendation [SOR]: B, meta-analysis of non−patient-oriented outcomes). Monitoring prostate-specific antigen (PSA), performing prostate digital rectal ...
  • Do intra-articular steroid injections affect glycemic control in patients with diabetes? 

    Kallock, Erin; Neher, Jon O.; St. Anna, Leilani (Family Physicians Inquiries Network, 2010)
    A single intra-articular steroid injection into the knee produces acute hyperglycemia for 2 or 3 days in patients with diabetes who otherwise have good glucose control (strength of recommendation [SOR]: B, small cohort ...
  • How should you treat the newly diagnosed hypertensive patient? 

    Debrino, Gary; Grover, Michael; Nichols, William (Family Physicians Inquiries Network, 2010-11)
    All hypertensive patients can potentially benefit from lifestyle interventions, including weight reduction, aerobic physical activity, the dietary approaches to stop hypertension (DASH) diet, and moderation of alcohol ...
  • Does DTC advertising affect physician prescribing habits? 

    Koch-Laking, Amber; Park, Michael K.; Tweed, Elizabeth M. (Family Physicians Inquiries Network, 2010-11)
    Direct-to-consumer advertising (DTCA) is associated with both higher fidelity to minimum treatment recommendations for depression and higher prescribing levels of antidepressants for depression and adjustment disorder ...
  • Which drugs are best when aggressive Alzheimer's patients need medication? 

    Mohundro, Brice L.; Pope, Karla; Shaw, Vincent; Hitchcock, Kristin (Family Physicians Inquiries Network, 2010-10)
    Atypical antipsychotics are an effective short-term (6-12 weeks) treatment for aggressive behavior in patients with Alzheimer's disease because they consistently decrease aggression scores (strength of recommendation ...
  • Does office spirometry improve quit rates in smokers? 

    Spata, Jennifer; Kelsberg, Gary; Safranek, Sarah (Family Physicians Inquiries Network, 2010-10)
    Simply performing spirometry and offering cessation advice doesn't improve quit rates in patients who smoke (strength of recommendation [SOR]: A, systematic review of randomized controlled trials [RCTs]). However, when the ...
  • What is the best noninvasive diagnostic test for women with suspected CAD? 

    Starr, Hillary; Powers, Laurel; Safranek, Sarah (Family Physicians Inquiries Network, 2010-09)
    Multidetector computed tomography (MDCT) may be the most sensitive and specific noninvasive diagnostic test for women with suspected coronary artery disease (CAD) (strength of recommendation [SOR]: A, multiple prospective ...
  • How can we keep impaired glucose tolerance and impaired fasting glucose from progressing to diabetes? 

    Swanson, Ana; Watrin, Kerry; Wilder, Laura (Family Physicians Inquiries Network, 2010-09)
    Lifestyle interventions aimed at weight loss of 5% to 10% of body weight along with moderate aerobic exercise such as brisk walking for 150 minutes a week are the most effective means to prevent impaired fasting glucose ...
  • Does exercise alleviate symptoms of depression? 

    Gill, Alan; Womack, Rosalind; Safranek, Sarah (Family Physicians Inquiries Network, 2010-09)
    Exercise reduces patient-perceived symptoms of depression when used as monotherapy (strength of recommendation [SOR]: B, meta-analysis of randomized controlled trials [RCTs] with significant heterogeneity). It relieves ...
  • Which drugs should post-MI patients routinely receive? 

    Lin, Victor; Holman, John R.; Jamieson, Barbara (Family Physicians Inquiries Network, 2010-09)
    patients should be placed on the following medications: antiplatelet agents (strength of recommendation [SOR]: A, meta-analysis for aspirin; A, multiple randomized controlled trials [RCTs] for aspirin plus clopidogrel) ...
  • What's the best way to manage upper extremity venous thrombosis? 

    Rabens, Clayton; Goodemote, Patricia; Jamieson, Barbara (Family Physicians Inquiries Network, 2010-08)
    Standard management is best: Start with unfractionated heparin or low-molecular-weight heparin and follow with long-term therapy with a vitamin K antagonist (strength of recommendation [SOR]: C, expert consensus and case ...
  • Which women should we screen for gestational diabetes mellitus? 

    Namak, Shahla; Lord, Richard W., Jr.; Zolotor, Adam J.; Kramer, Rochelle (Family Physicians Inquiries Network, 2010-08)
    It's unclear which women we should screen. No randomized controlled trials (RCTs) demonstrate that either universal screening or risk factor screening for gestational diabetes mellitus (GDM) prevents maternal and fetal ...
  • What is the most effective way to relieve symptoms of acute stress disorder? 

    Scott, James M., III; Nipper, Neil; Smith, Rita (Family Physicians Inquiries Network, 2010-08)
    Cognitive behavioral therapy (CBT) that emphasizes exposure-based treatment is the most effective intervention for adults with acute stress disorder (ASD) (strength of recommendation [SOR]: B, meta-analysis of limited-quality ...

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