Are oral anti-infective agents effective for pityriasis rosea?
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Are oral anti-infective agents effective for pityriasis rosea? Evidence-Based Answer: High-dose, oral acyclovir (800 mg 5 times daily for 7–10 days) appears effective in clearing the rash of pityriasis rosea (PR) and is superior to oral erythromycin in shortening the interval of the disease (SOR: B, RCTs). Erythromycin may be effective against PR (SOR: C, inconsistent RCTs).
Evidence Based Practice 17(5): E-12