Browsing 2014 UMKC Dissertations - Freely Available Online by Thesis Department "Cell Biology and Biophysics (UMKC)"
Now showing items 1-7 of 7
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Determining the differential roles of the dock family of GEFs in drosophila development
(2015-05-19)The evolutionarily conserved Dock proteins function as unconventional guanine nucleotide exchange factors (GEFs). Upon binding to ELMO (Engulfment and cell motility) proteins, Dock-ELMO complexes activate the Rho family ... -
Disconnecting a Role for DNA Repair in the Pathogenicity of the Human pathogen Cryptococcus neoformans
(2014)C. neoformans is an opportunistic fungal pathogen causing fatal meningitis and lung infections. Worldwide every year around 625,000 deaths occur due to Cryptococcosis. A basic understanding of Cryptococcus virulence ... -
Discovery of Enzymes Responsible for an Alternate Mevalonate Pathway in Haloferax volcanii
(2014-09-30)Archaea are a distinct evolutionary domain of microorganisms that contain isoprenoids in ether linkages to glycerol rather than the ester linked fatty acids that characterize membranes of bacteria or eukaryotes. Radiolabeling ... -
Mating Type Specific Roles During The Sexual Cycle Of Phycomyces Blakesleeanus
(2014)Phycomyces blakesleeanus is a filamentous fungus that belongs in the order Mucorales. It can propagate through both sexual and asexual reproduction. The asexual structures of Phycomyces called sporangiophores have served ... -
Regulation of Antimicrobial Peptide Genes in the Tobacco Hornworm Manduca sexta
(2015-05-26)The innate immune system, also known as natural or non-specific immune system, is conserved from insects to humans. The insect innate immune system is composed of humoral and cellular components. Insect humoral responses ... -
Regulation of Gene Expression by Non-coding RNAs in Arabidopsis and Brachypodium
(2014)Expansion of high-throughput sequencing technology has increased our understanding in the importance of pervasive transcription and the resulting indispensable molecules, noncoding RNAs (ncRNAs). A significant effort has ... -
Resveratrol Analogs: Potential Chemopreventive Agents in Breast Cancer
(2015-05-22)Epidemiological data and studies in rodent models strongly support the role of estrogens in the development of breast cancers. Estrogens have been added to the list of known human carcinogens. Exact mechanisms underlying ...