Browsing 2014 UMKC Dissertations - Freely Available Online by Thesis Department "Chemistry (UMKC)"
Now showing items 1-8 of 8
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Conformational and Structural Determinations of Substituted Four and Five Membered Rings by Infrared, Raman, and Microwave Spectral Studies
(2014)Studies of the structure and conformational stabilities of molecules have become increasingly important due in part to advances in the fields of biochemistry and nanochemistry. Specifically the conformation of organoamines ... -
Design, synthesis, characterization and photovoltaic applications of conjugated polymer hybrids containing coordinatively binded semiconducting nanocrystals
(2014-07-17)Orgainc-inorganic hybrids containing organic conjugated polymers and inorganic semiconducting nanocrystals are fascinating optoelectronic materials which may combine the advantages of both worlds. This dissertation aims ... -
Effects of Selected Contaminants on the Physical, Chemical, and Geotechnical Properties of Aquifer Solid
(2014)The primary objective of this study was to investigate the potential effects of hydrocarbons on the geotechnical properties of sand. A series of laboratory experiments were carried out to ascertain the influence of some ... -
Electronic, Optical, Structural, and Elastic Properties of MAX Phases and (Cr2Hf)2Al3C3
(2014-09-30)The term “MAX phase” refers to a very interesting and important class of layered ternary transition-metal carbides and nitrides with a novel combination of both metal- and ceramic-like properties that have made these ... -
Evaluation of siRNA mediated Silencing of IKKα in Prostate cancer and CD40 in Type-1 Diabetes
(2014-09-30)The objective of this dissertation is to present the various therapeutic approaches for two distinctly different diseases, prostate cancer and type-1 diabetes. Our objective (1) for prostate cancer is to evaluate the siRNA ... -
Novel Polycyclic Benzannulated Indole Scaffolds via Indole Aryne Cycloaddition, Pd (0)-Catalyzed Cross-coupling and ROM/RCM methodologies: Their Applications to Library Development and Drug Discovery
(2014)Dissertation under the direction of Keith R. Buszek, Ph.D., Professor of Chemistry, University of Missouri-Kansas City. Heterocyclic chemistry is one of the most valuable sources of novel compounds with diverse biological ... -
Ritonavir - A Novel Multidrug Resistance Modulator in Cancer Chemotherapy and Ocular Neovascular Diseases
(2014-08-28)Multidrug resistance (MDR), a clinical outcome characterized by subtherapeutic intracellular drug concentration, is one of the predominant factors limiting effective cancer chemotherapy. Several possible mechanisms and ... -
Role of Membrane Transporters in Drug Delivery, Drug Disposition And Drug-Drug Interactions
(2014-08-28)Tissues such as liver, kidney, brain and intestine expresses membrane transporters which play a vital role in drug absorption, distribution, metabolism and excretion. Understanding of functionality and molecular expression ...