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    • University of Missouri-Columbia
    • Graduate School - MU Theses and Dissertations (MU)
    • Theses and Dissertations (MU)
    • Dissertations (MU)
    • 2006 Dissertations (MU)
    • 2006 MU dissertations - Freely available online
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    Decreasing perinatal bovine leukosis virus infection in calves

    Nagy, Dusty W., 1970-
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    [PDF] short.pdf (9.232Kb)
    [PDF] research.pdf (364.5Kb)
    Date
    2006
    Format
    Thesis
    Metadata
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    Abstract
    Bovine leukosis virus (BLV) is an oncogenic retrovirus of cattle that causes lymphosarcoma in a proportion of infected individuals. Currently the United States estimates are that 44% of dairy cattle and 10% of beef cattle are infected with the virus. Many states have voluntary control programs in place, but no mandatory or federal programs currently exist. This is dramatically different from many other industrialized, cattle producing countries that have government controlled, mandatory control and eradication programs in place. The inability to accurately detect infection in calves by serologic test methods due to the interference of colostral immunoglobulin has led to US control programs focusing on the identification of infected adults. The ease at which serologic methods can be used in adults has also removed attention from the potential role that persistent lymphocytosis may play on an infected premise. The goal of this body of work was to develop alternative methods that may be utilized on heavily infected farms to help in the control of BLV infection. The studies presented here focus on the utility of diagnostic tests in the identification of infected calves and the identification of adults with persistent lymphocytosis. Serology, PCR, and the detection of lymphocytosis all have a place in control programs although the tests should not be used interchangeably. It is possible that providing colostrum with BLV specific antibodies is protective against infection in neonatal calves.
    URI
    https://doi.org/10.32469/10355/4345
    https://hdl.handle.net/10355/4345
    Degree
    Ph. D.
    Thesis Department
    Veterinary pathobiology area program (MU)
    Rights
    OpenAccess.
    Collections
    • 2006 MU dissertations - Freely available online
    • Veterinary Pathobiology electronic theses and dissertations (MU)

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