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dc.contributor.advisorNair, Satish S., 1960-eng
dc.contributor.authorJang, Tai Seung, 1971-eng
dc.date.issued2006eng
dc.date.submitted2006 Falleng
dc.descriptionThe entire dissertation/thesis text is included in the research.pdf file; the official abstract appears in the short.pdf file (which also appears in the research.pdf); a non-technical general description, or public abstract, appears in the public.pdf file.eng
dc.descriptionTitle from title screen of research.pdf file (viewed on August 2, 2007)eng
dc.descriptionVita.eng
dc.descriptionIncludes bibliographical references.eng
dc.descriptionThesis (Ph. D.) University of Missouri-Columbia 2006.eng
dc.descriptionDissertations, Academic -- University of Missouri--Columbia -- Mechanical and aerospace engineering.eng
dc.description.abstractModeling approaches are developed for two different levels, cellular (Part I) and systems (Part II), and used to develop insights into system performance. PART I consists of three chapters focusing on computational neuroscience models at cellular level. The mechanisms of action of a drug on prefrontal cortical cells are elucidated with two possible hypotheses, and a systematic methodology to study the excitability of cells under inhibitory post synaptic currents (IPSCs) is developed. PART II focuses on mathematical models at the systems level. Specifically, thermal physiology models of the entire human body are developed using statistical and black box (artificial neural network, ANN) techniques.The MU 2-D Man, a human thermal model has been developed for designing an automatic thermal comfort control strategy for NASA astronaut space suits and for the US Air Force warfighters in chemo-bio suits. The model has been enhanced using more accurate modeling of digits incorporating arterio-venous anastomoses (AVA) mechanisms that the fingers and toes use for better control of heat transfer.eng
dc.identifier.merlin.b59270081eng
dc.identifier.oclc162139859eng
dc.identifier.otherJangT-120806-D6054eng
dc.identifier.urihttp://hdl.handle.net/10355/4350eng
dc.languageEnglisheng
dc.publisherUniversity of Missouri--Columbiaeng
dc.relation.ispartofcollectionUniversity of Missouri-Columbia. Graduate School. Theses and Dissertations.eng
dc.subject.lcshComputational neuroscienceeng
dc.subject.lcshSpace biologyeng
dc.subject.lcshLife support systems (Space environment)eng
dc.subject.lcshExtravehicular space suitseng
dc.titleSpecific bio-modeling and analysis techniques at cellular and systems leveleng
dc.typeThesiseng
thesis.degree.disciplineMechanical and aerospace engineering (MU)eng
thesis.degree.grantorUniversity of Missouri--Columbiaeng
thesis.degree.levelDoctoraleng
thesis.degree.namePh. D.eng


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