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dc.contributor.advisorNair, Satish S., 1960-en
dc.contributor.authorJang, Tai Seung, 1971-en_US
dc.date.issued2006eng
dc.date.submitted2006 Fallen
dc.descriptionThe entire dissertation/thesis text is included in the research.pdf file; the official abstract appears in the short.pdf file (which also appears in the research.pdf); a non-technical general description, or public abstract, appears in the public.pdf file.en_US
dc.descriptionTitle from title screen of research.pdf file (viewed on August 2, 2007)en_US
dc.descriptionVita.en_US
dc.descriptionIncludes bibliographical references.en_US
dc.descriptionThesis (Ph. D.) University of Missouri-Columbia 2006.en_US
dc.descriptionDissertations, Academic -- University of Missouri--Columbia -- Mechanical and aerospace engineering.en_US
dc.description.abstractModeling approaches are developed for two different levels, cellular (Part I) and systems (Part II), and used to develop insights into system performance. PART I consists of three chapters focusing on computational neuroscience models at cellular level. The mechanisms of action of a drug on prefrontal cortical cells are elucidated with two possible hypotheses, and a systematic methodology to study the excitability of cells under inhibitory post synaptic currents (IPSCs) is developed. PART II focuses on mathematical models at the systems level. Specifically, thermal physiology models of the entire human body are developed using statistical and black box (artificial neural network, ANN) techniques.The MU 2-D Man, a human thermal model has been developed for designing an automatic thermal comfort control strategy for NASA astronaut space suits and for the US Air Force warfighters in chemo-bio suits. The model has been enhanced using more accurate modeling of digits incorporating arterio-venous anastomoses (AVA) mechanisms that the fingers and toes use for better control of heat transfer.en_US
dc.identifier.merlin.b59270081en_US
dc.identifier.oclc162139859en_US
dc.identifier.otherJangT-120806-D6054en_US
dc.identifier.urihttp://hdl.handle.net/10355/4350
dc.publisherUniversity of Missouri--Columbiaen_US
dc.relation.ispartof2006 Freely available dissertations (MU)en_US
dc.relation.ispartofcommunityUniversity of Missouri-Columbia. Graduate School. Theses and Dissertations. Dissertations. 2006 Dissertations
dc.subject.lcshComputational neuroscienceen_US
dc.subject.lcshSpace biologyen_US
dc.subject.lcshLife support systems (Space environment)en_US
dc.subject.lcshExtravehicular space suitsen_US
dc.titleSpecific bio-modeling and analysis techniques at cellular and systems levelen_US
dc.typeThesisen_US
thesis.degree.disciplineMechanical and aerospace engineeringen_US
thesis.degree.disciplineMechanical and aerospace engineeringeng
thesis.degree.grantorUniversity of Missouri--Columbiaen_US
thesis.degree.levelDoctoralen_US
thesis.degree.namePh. D.en_US


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