Are low-carbohydrate diets safe and effective in patients with obesity-related diseases?
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Evidence-based answer: Compared with low-fat/high-carbohydrate (conventional) diets, low-carbohydrate/ high-protein (LC/HP) diets are at least as effective in reducing weight and blood pressure with limited side effects and no severe adverse events. Triglyceride reduction and high-density lipoprotein (HDL) elevation appear to be superior to conventional diets (SOR: C, disease-oriented outcomes from systematic review of RCTs and consistent RCT).
Evidence Based Practice 17(6): 1-2.