What are the safest and most effective malarial drugs to reduce antenatal malaria?
What are the safest and most effective malarial drugs to reduce antenatal malaria? Evidenced-based answer : Prophylactic administration of antimalarial drugs reduces the risk of antenatal malaria. Proguanil and sulfadoxine-pyrimethamine are more effective than chloroquine (SOR: A, Cochrane review and RCT). A 3-dose strategy with sulfadoxine-pyrimethamine is more effective than a 2-dose strategy (SOR: B, RCT).
Evidence Based Practice 17(8): E9-E10