Do progestin-only oral contraceptives increase cardiovascular risk?
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Do progestin-only oral contraceptives increase cardiovascular risk? Evidence-based answer : Probably not. Progestogen or progestin-only contraceptive (POC) use does not appear to be associated with an increased risk of cardiovascular disease (CVD), venous thromboembolism (VTE), thromboembolic stroke, or acute myocardial infarction. (SOR: B, meta-analysis and individual case-control studies). There may be an increased risk of VTE among injectable progestin users (SOR: C, subgroup analysis in a meta-analysis of observational studies).
Evidence Based Practice 17(8): E14