dc.contributor.advisor | Sun, Jianguo, 1961- | eng |
dc.contributor.author | Wang, Lianming, 1977- | eng |
dc.date.issued | 2006 | eng |
dc.date.submitted | 2006 Summer | eng |
dc.description | The entire dissertation/thesis text is included in the research.pdf file; the official abstract appears in the short.pdf file (which also appears in the research.pdf); a non-technical general description, or public abstract, appears in the public.pdf file. | eng |
dc.description | Title from title screen of research.pdf file viewed on (May 2, 2007) | eng |
dc.description | Vita. | eng |
dc.description | Thesis (Ph.D.) University of Missouri-Columbia 2006. | eng |
dc.description.abstract | Interval-censored failure time data commonly arise in clinical trials and medical studies. In such studies, the failure time of interest is often not exactly observed, but known to fall within some interval. For multivariate interval-censored data, each subject may experience multiple events, each of which is interval-censored. This thesis studies four research problems related to regression analysis and association study of multivariate interval-censored data. In particular, in Chapter 2, we propose a goodness-of-fit test for the marginal Cox model approach, which is the most commonly, used approach in multivariate regression analysis. Chapter 3 presents a two-stage estimation procedure for the association parameter for case 2 bivariate interval-censored data. In Chapter 4 we give a simple procedure to estimate the regression parameter for case 2 interval-censored data and Chapter 5 studies the efficient estimation of regression parameters and association parameter simultaneously for bivariate current status data. All the proposed methods are assessed by simulation studies and illustrated using real-life applications. | eng |
dc.description.bibref | Includes bibliographical references. | eng |
dc.identifier.merlin | b58485806 | eng |
dc.identifier.oclc | 123911987 | eng |
dc.identifier.uri | https://doi.org/10.32469/10355/4375 | eng |
dc.identifier.uri | https://hdl.handle.net/10355/4375 | |
dc.language | English | eng |
dc.publisher | University of Missouri--Columbia | eng |
dc.relation.ispartofcommunity | University of Missouri--Columbia. Graduate School. Theses and Dissertations | eng |
dc.rights | OpenAccess. | eng |
dc.subject.lcsh | Failure time data analysis | eng |
dc.subject.lcsh | Regression analysis | eng |
dc.title | Statistical analysis of multivariate interval-censored failure time data | eng |
dc.type | Thesis | eng |
thesis.degree.discipline | Statistics (MU) | eng |
thesis.degree.grantor | University of Missouri--Columbia | eng |
thesis.degree.level | Doctoral | eng |
thesis.degree.name | Ph. D. | eng |