What is the best management of thyroid nodules less than 1 cm in size?
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What is the best management of thyroid nodules less than 1 cm in size? All thyroid nodules, regardless of size, should initially be worked up with thyroid-stimulating hormone (TSH) measurement and ultrasound (US). US-guided fineneedle aspiration (US-FNA) should be performed on nodules if on US they are hypoechoic and have one of the following concerning characteristics: microcalcifications, irregular margins, or intralesional vascular markings. Nodules lacking these characteristics (or if found to be benign after FNA and cytology) can be followed with serial US (every 6–18 months) (SOR: C, cohort trial and evidence-based guidelines).
Evidence Based Practice 17(10): E9-E10