Which risk factors and signs and symptoms are associated with coccidioidomycosis?

Abstract

Q: Which risk factors and signs and symptoms are associated with coccidioidomycosis? Evidence-Based Answer: Risk factors for coccidioidomycosis, or valley fever, include lower respiratory tract symptoms lasting longer than 14 days, chest pain, rash, having lived in endemic areas fewer than 10 years, and diabetes mellitus or immunosuppressive conditions (strength of recommendation [SOR]: B, several prospective cohort and case-control studies). The most common signs and symptoms include cough (74%), fever (56%), night sweats (35%), pleuritic chest pain (33%), chills (28%), dyspnea (27%), weight loss (21%), and rash (14%) (SOR: B, retrospective cohort study).