What is the best treatment for ankylosing spondylitis?
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What is the best treatment for ankylosing spondylitis? Evidence-based answer: Both tumor necrosis factor α (TNFα) blockers and NSAIDs have positive effects on ankylosing spondylitis patients’ global assessment, pain, physical function, and morning stiffness (SOR: A, meta-analysis of RCTs). NSAIDs are recommended as first-line medications and TNFα blockers are recommended for patients with persistently high disease activity despite conventional therapy (SOR: B, evidence-based guidelines).
Evidence Based Practice 18(2): 1-2