What is the safest treatment for constipation in children?
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What is the safest treatment for constipation in children? Bottom line: Many laxatives are used to treat childhood constipation, and it is unclear which treatment is safest because not all laxatives have been compared in head-to-head trials. Polyethylene glycol (PEG), often used as a firstline treatment, has been shown to be safe and more comfortable than enemas. PEG and lactulose have rates of adverse effects similar to placebo. PEG, Milk of Magnesia, and fiber mixtures all can cause dose-related diarrhea (SOR: B, based on RCTs and systemic reviews with consistent findings).
Evidence Based Practice 18(2): 6