What is the best treatment for low HDL?
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What is the best treatment for low HDL? Evidence-Based Answer: No high-quality evidence is available regarding the impact of a low-fat diet for patients with low high-density lipoprotein (HDL). Moderate alcohol consumption may slightly increase HDL levels by less than 0.1 mmol/L. Medications including fibrates and HMG-CoA reductase inhibitors increase HDL by 3% to 10% (SOR: C, diseaseoriented outcomes). In patients with both low HDL and low LDL with cardiovascular risk factors, pravastatin therapy reduces cardiovascular events by 4% over 6 years (SOR: B, RCT).
Evidence Based Practice 18(2): 13