In patients with sleep apnea, does CPAP improve long-term cardiovascular outcomes?
In patients with sleep apnea, does CPAP improve long-term cardiovascular outcomes? Evidence-Based Answer: Yes. In patients with obstructive sleep apnea (OSA), continuous positive airway pressure therapy (CPAP) is associated with a reduction in cardiovascular mortality to levels similar to patients without OSA (SOR: B, meta-analysis of cohort studies). Furthermore, CPAP treatment is associated with fewer new cardiovascular events in patients with OSA and coronary artery disease (CAD) (SOR: B, cohort study). CPAP also results in small improvements in left ventricular ejection fraction (LVEF) in patients with both OSA and heart failure (HF) (SOR: C, meta-analysis of RCTs with disease-oriented evidence).
Evidence Based Practice 18(4): 12