dc.contributor.author | Freund, Jeffrey | eng |
dc.contributor.author | Kraus, Connie | eng |
dc.contributor.author | Hooper-Lane, Christopher | eng |
dc.date.issued | 2015 | eng |
dc.description.abstract | Q: How effective are opioids for chronic low back pain? Evidence-based answer: Short-term (<4 months) treatment with opioids provides modest relief of chronic low back pain, but only minimal improvement in function compared with placebo (strength of recommendation [SOR]: B, systematic review of lower-quality randomized controlled trials [RCTs]). Tramadol isn't superior to nonsteroidal anti-inflammatory drugs (NSAIDs) for pain relief (SOR: A, consistent results from RCTs). In addition, oxycodone with titrated morphine isn't better than naproxen for relieving pain or improving function (SOR: C, a low-quality RCT). Although no long-term RCTs have been done, cohort studies have shown that 6 to 12 months of opioid use is associated with a small decrease in pain and either very minimal improvement in, or worsening of, disability (SOR: B, prospective cohort trials). | eng |
dc.identifier.uri | https://hdl.handle.net/10355/46755 | eng |
dc.language | English | eng |
dc.publisher | Family Physicians Inquiries Network | eng |
dc.relation.ispartofcollection | Clinical Inquiries, 2015 (MU) | eng |
dc.relation.ispartofcommunity | University of Missouri--Columbia. School of Medicine. Department of Family and Community Medicine. Family Physicians Inquiries Network | eng |
dc.relation.ispartofseries | Journal of family practice, 64, no. 09 (September 2015): 584-585. | eng |
dc.rights | OpenAccess. | eng |
dc.rights.license | This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 3.0 License. | eng |
dc.subject | Research Subject Categories | eng |
dc.title | How effective are opioids for chronic low back pain? | eng |
dc.type | Article | eng |