Earlier peanut exposure reduces risk of peanut allergy in high-risk children
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In this open-label RCT, 4- to 11-month-old children at high risk of developing peanut allergy were divided into 2 cohorts based on response to a skin-pinprick test (SPT). Children with negative SPT (n=542) were randomized to avoid (n=270) or consume (n=272) peanuts until 60 months of age. Children with positive SPT (n=98) were also randomized to avoid (n=51) or consume (n=47) peanuts. Consumption was defined as at least 6 grams of peanut protein consumed per week in the form of Bamba® (peanut butter and puffed maize snack food) or smooth peanut butter.
Evidence Based Practice 18(9): 4