Browsing Pharmacology & Toxicology Theses and Dissertations (UMKC) by Thesis Semester "2018 Fall"
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Preparation of Pentablock Nanomicellar Formulations for Prostate Cancer Drug Delivery Systems
(University of Missouri -- Kansas City, 2018)This study is divided into three specific aims. Specific aim #1 focused on synthesis of pentablock co-polymer using monomers of L-lactide, ε-caprolactone and ethylene-glycol with varied molecular weights, (ii) ... -
Role of Redox-Active Trace Metal (RATM) Oxidants in the Regulation of Toll-Like Receptor 4 (TLR4) Signaling-Mediated Inflammatory Phenotype in Synovial Fibroblasts
(University of Missouri -- Kansas City, 2018)While the involvement of oxidant stress in rheumatoid arthritis (RA) has been suspected, the role of redox-active trace metals (RATM) as exogenous pro-oxidants in the pathogenesis of RA has not yet been investigated. ...