Are rates of neonatal herpes reduced if pregnant mothers are screened for HSV?
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Are rates of neonatal herpes reduced if pregnant mothers are screened for HSV? Evidence-based answer: No direct evidence suggests screening pregnant women for herpes simplex virus (HSV) reduces neonatal herpes infection. Several decision analyses indicate that screening, when accompanied by counseling or antiviral treatment, may reduce neonatal herpes by about 20% to 80%; however, these strategies are costly (SOR: C, based on decision support analyses and expert opinion). While some experts recommend HSV screening based on risk factors, targeted testing may not identify a significant proportion of mothers whose infants are at high risk of acquiring herpes at birth (SOR: C, based on expert opinion and a large case-control study).
Evidence Based Practice 18(12): 1-2