Browsing 2016 Dissertations (UMKC) by Thesis Department "Molecular Biology and Biochemistry (UMKC)"
Now showing items 1-5 of 5
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Identification of a Novel Link between the Motor Proteins Dynein and Kinesin-1
(University of Missouri–Kansas City, 2016)The motor proteins dynein and kinesin are fascinating biological machines which, like vehicles in a city, move various cellular cargoes along cytoskeletal microtubules (MT). In filamentous fungi, these motors are important ... -
An Investigation into the Effects of Alterations in Ribosomal Proteins S4 and S5 on Translational Accuracy, Ribosomal RNA Processing, and Ribosome Assembly
(University of Missouri--Kansas City, 2016)Accurate translation of genetic message is an essential step in gene expression and is carried out by the ribosome. Ribosomal proteins S4 and S5 are critical for the decoding and the assembly processes on the ribosome. The ... -
Structural Basis for the Formation of PTPRG•CNTN Complexes in Neural Tissues
(2016)Receptor protein tyrosine phosphatase gamma (PTPRG) is a cell surface receptor expressed primarily on neurons. It combines cytoplasmic tyrosine phosphatase domains and an extracellular region that includes a carbonic ... -
The Ins and Outs and ABCs of Antifungal Drug Transport: Characterizing the Role of Membrane Transporters in Pathogenic Fungi
(2016)Pathogenic fungi cause serious disease and even death in humans, animals and plants. In medicine and agriculture alike, fungal infections are widespread and represent a significant threat to global public health. The ... -
The Molecular Mechanisms of Antifungal Drug Resistance In Pathogenic Fungi
(2016)Pathogenic fungi including Candida albicans, cause oral, systemic, and vaginal infections, mostly in immune-compromised individuals. Azoles are the most common antifungals used in treating these infections. The most ...