2016 Dissertations (UMKC): Recent submissions
Now showing items 1-20 of 75
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The effects of HIV-1 viral protein r (vpr) and anti-retroviral drugs in the brain: Implications in HIV-1 associated neurocognitive disorders
(University of Missouri--Kansas City, 2016)The morbidity and mortality of HIV-1 infected individuals has declined significantly by the introduction of highly active antiretroviral therapy (HAART). Nevertheless, different forms of HIV-1 associated neurocognitive ... -
Silicon on Ferroelectric Insulator Field Effect Transistor (SOFFET): A Radical Alternative to Overcome the Thermionic Limit
(University of Missouri--Kansas City, 2016)The path of down-scaling traditional MOSFET is reaching its technological, economic and, most importantly, fundamental physical limits. Before the dead-end of the roadmap, it is imperative to conduct a broad research ... -
Discovery of Peptide and Aptamer Ligands for Targeted Drug Delivery to Hepatic Stellate Cells
(University of Missouri--Kansas City, 2016)The objective of this dissertation is to present two approaches to identify Hepatic Stellate Cells (HSCs) targeting ligands using phage-display library biopanning and systematic evolution of ligands by exponential ... -
Internet of Things (IoT) Applications With Diverse Direct Communication Methods
(University of Missouri--Kansas City, 2016)Internet of Things (IoT) is a network of physical objects or things that are embedded with electronics, software, sensors, and network connectivity - which enable the object to collect and exchange data. Rapid proliferation ... -
Graphene Nanotechnology the Next Generation Logic, Memory and 3D Integrated Circuits
(University of Missouri--Kansas City, 2016)Floating gate transistor is the basic building block of non-volatile flash memory, which is one of the most widely used memory gadgets in modern micro and nano electronic applications. Recently there has been a surge ... -
Novel Approaches for Targeted Delivery of Cancer Therapeutics to Nuclei of Malignant Cells
(University of Missouri--Kansas City, 2016)The primary goal of this project is to increase specific uptake of anti-cancer therapeutics by nuclei of cancer cells. A lot of research has been done to target therapeutics specifically across plasma membrane of ... -
Formulation of Hyaluronidase Enzyme Sensitive Topical Nanomicrobicides for HIV Virus Transmission Prevention
(University of Missouri--Kansas City, 2016)The objective of this dissertation is to design and optimize a nanoformulations (nanoparticle and nanofiber) delivery system loaded with anti-HIV topical microbicides for HIV prevention in women. In chapters 1 and ... -
Ultra Low Power SubThreshold Device Design Using New Ion Implantation Profile
(University of Missouri--Kansas City, 2016)One of the important aspects of integrated circuit design is doping profile of a transistor along its length, width and depth. Devices for super-threshold circuit usually employ halo and retrograde doping profiles in ... -
Development and Evaluation of Nanocarriers against Atherosclerosis
(University of Missouri--Kansas City, 2016)The objective of this project was to develop advanced nanocarriers such as nanographene and graphene quantum dots against atherosclerosis. Mannosylated-reduced graphene oxide (Man-rGO) was developed as a targeted ... -
Essays on Complexity and Design Thinking in Entrepreneurship
(University of Missouri--Kansas City, 2016)The New venture creation context is experiencing unprecedented change. Rapid shifts in technology, customer needs, and institutions have translated into a very complex, uncertain, and dynamic landscape, for those who ... -
Simulating Urban Landscape Transformation: Implications for Urban Wetlands at Multiple Scales
(University of Missouri--Kansas City, 2016)Urban landscape change simulation has received increasing attention in recent times. As a result, many studies have focused on various aspects of land change simulation, ranging from uncertainty of input data to model ... -
Investigation of Interconnect and Device Designs for Emerging Post-MOSFET and Beyond Silicon Technologies
(University of Missouri--Kansas City, 2016)The integrated circuit industry has been pursuing Moore’s curve down to deep nanoscale dimensions that would lead to the anticipated delivery of 100 billion transistors on a 300 mm² die operating below 1V supply in the ... -
A Spatial Theory of School Closure: An Examination of School Closure in America
(University of Missouri--Kansas City, 2016)This dissertation seeks to uncover the primary factors associated with public school closure in the United States during the five year period 2007 – 2012. Specifically, it addresses three questions related to school closures. ... -
Practical Applications of Infrared, Raman and Nuclear Magnetic Resonance Spectroscopic Techniques for Qualitative, Quantitative and Structural Analysis of Pharmaceutical Drugs, Cementitious Material and Organic Molecules Containing Phosphorous
(University of Missouri--Kansas City, 2016)The study of the interaction between matter and electromagnetic radiation which procreated the wide branch named as Spectroscopy has gained tremendous attention since the last century. Atoms and molecules respond to ... -
Commodity Based Sovereign Wealth Funds: An Alternative Path to Economic Development
(University of Missouri--Kansas City, 2016)Natural resource producing countries struggle with issues about how to make use of their natural resources properly, allocate the funds from these resources and how to ensure continuity of th ... -
Drinking Water Treatment Waste as an Alternative for Internal Curing and Cement Replacement in Concrete
(University of Missouri--Kansas City, 2016)Concrete can be a highly durable construction material when permeability is low. Hydrating cement paste shrinks through several mechanisms broadly grouped into autogenous and drying shrinkage. These mechanisms cause cracks ... -
An Investigation into the Effects of Alterations in Ribosomal Proteins S4 and S5 on Translational Accuracy, Ribosomal RNA Processing, and Ribosome Assembly
(University of Missouri--Kansas City, 2016)Accurate translation of genetic message is an essential step in gene expression and is carried out by the ribosome. Ribosomal proteins S4 and S5 are critical for the decoding and the assembly processes on the ribosome. The ... -
Breaking the Silence: A Qualitative Critical Autoethnography of a Principal's Lived Experience with Having Courageous Conversations about Race
(University of Missouri--Kansas City, 2016)This qualitative critical autoethnography represents a highly personalized account of the intricacies and reflections of a Black female educational leader engaging in courageous conversations about race with a predominately ... -
Design Guidelines, Scan Behavior and Characteristic Mode Analysis for a Class of Ultra-Wideband Microstrip Patch Antennas
(University of Missouri--Kansas City, 2016)Ultra-wideband (UWB), low-profile microstrip patch antennas and phased arrays have their niche in many wireless communication and medical applications. In recent years, the U-slot patch antenna established itself as a ... -
Application of Ab Initio Calculations and Molecular Dynamics to Collagen and Brome Mosaic Virus
(University of Missouri--Kansas City, 2016)Molecular Dynamics (MD) simulations are no more accurate than the underlying force field which represents the molecular interactions. In this thesis, we have calculated ab initio atomic partial charges for proteins of ...