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dc.contributor.authorKelsberg, Garyeng
dc.contributor.authorMaragh, Leticiaeng
dc.contributor.authorSafranek, Saraheng
dc.date.issued2016-05eng
dc.description.abstractQ: Which nonhormonal treatments are effective for hot flashes? Evidence-based answer: Selective serotonin reuptake inhibitors (SSRIs [fluoxetine, sertraline, paroxetine]) and the selective norepinephrine reuptake inhibitor (SNRI) venlafaxine, as well as clonidine and gabapentin, reduce hot flashes by about 25% (approximately one per day) in women with and without a history of breast cancer. No studies compare medications against each other to determine a single best option (strength of recommendation [SOR]: A, systematic reviews and meta-analyses of randomized controlled trials [RCTs]). In comparison, estrogen reduces the frequency of hot flashes by about 75%, or 2.5 to 3 per day. The phytoestrogens (soy isoflavones, red clover extract, black cohosh), vitamin E, and nonpharmacologic measures (relaxation therapy, exercise, acupuncture, homeopathy, magnet therapy) lack evidence of effectiveness (SOR: A, meta-analyses of RCTs, many of which were low quality).eng
dc.identifier.citationJournal of Family Practice, 66(05) 2016: E1-E3.eng
dc.identifier.urihttps://hdl.handle.net/10355/49259
dc.languageEnglisheng
dc.publisherFamily Physicians Inquiries Networkeng
dc.relation.ispartofseriesClinical inquiries, 2016eng
dc.relation.ispartofseriesJournal of Family Practice, vol. 65, no. 05 (2016)eng
dc.rightsOpenAccess.eng
dc.rights.licenseThis work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 3.0 License.eng
dc.subjecthot flashes ; treatments ; menopause ; women ; breast cancereng
dc.titleWhich nonhormonal treatments are effective for hot flashes?eng
dc.typeArticleeng


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