What is the best treatment strategy to heal and prevent recurrence of acute esophagitis in the elderly?
Proton pump inhibitors (PPIs) are significantly more effective than H2-receptor antagonists (H2RA) for healing esophagitis in the elderly within the first 8 weeks (SOR: A, meta-analysis of 2 RCTs). Treatment with a low-dose PPI for 6 more months after initial treatment of 6 months is better than placebo for prevention of recurrence of esophagitis (SOR: B, RCT).
Evidence-Based Practice 19, no. 4 (2016): 12-13