Is adding clopidogrel to aspirin more effective than aspirin alone for reducing the risk of recurrent strokes?
Clopidogrel plus aspirin is more effective than aspirin alone for reducing recurrent strokes in patients who have had an ischemic stroke or transient ischemic attack (TIA). There are no significant differences in risk of bleeding (SOR: A, meta-analysis of RCTs and single RCT). However, it is unclear if the combination is more effective than clopidogrel alone.
Evidence-Based Practice 19, no. 4 (2016): 13, 15