In patients who have had a renal transplant, what medication factors influence the incidence and management of hypertension?
Calcium channel blockers (CCBs) reduce the risk of graft loss after renal transplant by 25% compared with placebo; no antihypertensive class decreases mortality (SOR: A, meta-analysis of RCTs). Hypertension (HTN) may be more common after transplant in patients treated with cyclosporine compared with tacrolimus SOR: C, meta-analysis of RCTs with nonsignificant results).
Evidence-Based Practice 19, no. 6 (2016): 8-9