Are oral anti-allergy treatments as effective as injection immunotherapy (allergy shots)?
Are oral anti-allergy treatments as effective as injection immunotherapy (allergy shots)? Evidence-based answer: Subcutaneous immunotherapy (SCIT) is more effective than sublingual immunotherapy (SLIT) for decreasing symptoms and medication use in patients with allergic rhinoconjunctivitis due to environmental allergies, but likely not for grass pollen allergy specifically (SOR B, systematic reviews of RCTs with heterogeneous outcomes). Direct head-to-head studies of SLIT and SCIT are lacking.
Evidence-Based Practice 19, no. 7 (2016): E4