RSS 1.0Department of Chemistry (MU)
The Department of Chemistry at the College of Arts and Sciences University of Missouri-Columbia offers Graduate and Undergraduate degree programs and houses multiple research facilities.
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In vitro characterization of metal-binding and glutathione-binding proteins and their potential use to study transition metal homeostasis in plants
(University of Missouri--Columbia, 2017)Protein purification is vital for the characterization of the function, structure, and interactions of a protein.(Berg et al. 2002) Before a specific protein can be identified and characterized, the protein is extracted ... -
Formation of water channels in the crystalline hydrates of macrocyclic compounds [dataset]
(2018)RSP and matrix zip files contain .sfrm files that have both the photographic data and metadata desicribing the instrument, readable with scientific software. The work zip file subfolder contains a .p4p file generated after ... -
Hypoxia-selective antitumor prodrugs and fluorescent probes
(University of Missouri--Columbia, 2016)Hypoxia-selective antitumor prodrugs utilize the unique feature of most tumors -- hypoxia (low oxygen concentration), for therapeutic purpose and are widely studied in preclinical and clinical stages. Tirapazamine (TPZ, ... -
Synthesis design and nuclear medicine applications for radiometal, beta and gamma emission, chelated complexes
(University of Missouri--Columbia, 2017)Nuclear medicine covers a wide variety of radionuclides to meet demands of disease. In the current study, first we have looked at the application of mono-amine mono-amide ligands for Re(V), 99mTc(V), and 186Re(V) with ... -
Near infrared fluorescent sensors and their use in vivo
(University of Missouri--Columbia, 2017)In an effort to design near-infrared (NIR), water soluble glucose sensors, several pH sensitive NIR cyanine derivates were designed and synthesized to provide insight into the viability of the cyanine platform as the ... -
MC-ICP-MS analysis of uranium and plutonium in keratinous samples for the purposes of nuclear forensic and biomarker establishment
(University of Missouri--Columbia, 2017)One objective of nuclear forensics is to identify the source of interdicted nuclear materials in order to help ensure the safety and security of special nuclear materials. Since 1995, The International Atomic Energy Agency ... -
Polystyrene coated iron-platinum drug delivery platforms for theranostics
(University of Missouri--Columbia, 2016)[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Cancer is the second leading cause of death in the United States, exceeded only by heart disease, and it is estimated that one in every four deaths is ... -
Structural studies of type B proline utilization A (PutA) proteins
(University of Missouri--Columbia, 2016)[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] This thesis addresses the structural studies of the type B proline utilization A (PutA) proteins. Proline utilization A (PutA) catalyzes the oxidation ... -
Iron-platinum nanoparticles as multifunctional vehicles in imaging and drug delivery
(University of Missouri--Columbia, 2016)[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] In the United States alone, approximately 1.6 million people are diagnosed with cancer and over 500,000 people die of cancer each year. According to ... -
Economical synthesis of carbon nanoparticles
(University of Missouri--Columbia, 2016) -
Mechanistic and computational studies of ferroin, simple organic acids, and bromine oxides : elucidating the complex electrochemical dance in an oscillating reaction
(University of Missouri--Columbia, 2016) -
LC-MS/MS method development for quantification of bioactive compounds in elderberry and garlic botanicals
(University of Missouri--Columbia, 2016)Elderberry (Sambucus nigra spp.) juice contains a variety of polyphenols mostly anthocyanins. In order to understand the variation of polyphenol levels by genotype, various elderberry juice samples were analyzed for total ... -
Crystal engineering of supramolecular complexes based on pyrogallol[4]arenes
(University of Missouri--Columbia, 2016)Crystal engineering primarily deals with the understanding of intermolecular interactions in the context of crystal packing and thus utilizes this information for the designing and development of novel crystalline solid ... -
Nuclear forensic applications of uranium oxide chemistry and morphology
(University of Missouri--Columbia, 2015)[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] The entire nuclear fuel cycle is a chemistry-intensive process, from accessing the raw materials from ore, to enriching and forming the fuels, to the ... -
Fluorescent sensors for the detection of glucosamine and thiaminase
(University of Missouri--Columbia, 2015)[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Fluorescence chemical sensing is a highly important tool in science and industry with many applications in pharmaceutical screening, cell respiration, ... -
Synthesis and properties of small molecules designed to covalently capture native and oxidized forms of protein tyrosine phosphatase 1B (PTP1B)
(University of Missouri--Columbia, 2016)[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Protein tyrosine phosphatase 1B (PTP1B) is a validated target for the treatment of type 2 diabetes and obesity. The discovery of selective inhibitors ... -
Gold-coated lanthanide phosphate nanoparticles for targeted radiotherapy
(University of Missouri--Columbia, 2016)The success of a targeted radiotherapy system depends on its ability to carry and deliver its radioactive payload to a specific site. Lanthanide phosphate nanoparticles are highly stable in a variety of solvents. By ... -
A study of interpolating moving least-squares method on fitting potential energy surface
(University of Missouri--Columbia, 2016)Interpolating moving least-squares method (IMLS) is a highly accurate fitting method. There are a lot of studies on how to use IMLS to fit potential energy surfaces (PESs). However, there are still only few IMLS-fitted ... -
Technetium and rhenium (I and V) complexes for radiopharmaceutical applications
(University of Missouri--Columbia, 2016)Technetium and rhenium have radioactive isotopes that are clinically useful for diagnostic (Tc-99m) or therapeutic (Re-186/188) purposes. This makes them attractive candidates for incorporation into pharmaceuticals. One ... -
Small molecule-based approaches toward elucidation of structure and properties of abasic site-derived interstrand DNA crosslinks
(University of Missouri--Columbia, 2016)[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Damage to DNA is both a naturally occurring and environmentally induced process that can have serious biological consequences, such as mutation and ...