RSS 1.0Department of Chemistry (MU)
The Department of Chemistry at the College of Arts and Sciences University of Missouri-Columbia offers Graduate and Undergraduate degree programs and houses multiple research facilities.
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The use of pluripotent stem cells as a model for early human placentation
(University of Missouri--Columbia, 2018)Throughout gestation, the placenta plays a critical role in ensuring proper development of the fetus. The placenta functions to exchange nutrients, oxygen, and fetal waste, produce and secrete hormones to influence maternal ... -
Arsenic-72, 77 as a matched pair radiopharmaceutical for imaging and radiotherapy
(University of Missouri--Columbia, 2018)Radiopharmaceuticals deliver radionuclides to specific target sites via the bifunctional chelate approach, where the radionuclides are chelated with a ligand and linked to a targeting biomolecule. They can be categorized ... -
Development of radiolabeled metal chalcogenide nanoparticles for targeted adiotherapy against an infection
(University of Missouri--Columbia, 2018)Targeted radiotherapy has been demonstrated to be therapeutic against infections with doses comparable to what a patient would receive for cancer treatment. The aim of this research to create a platform for targeted ... -
Studies and synthetic methodology of Nampt inhibition
(University of Missouri--Columbia, 2018)The purpose of this research is to study and synthesize an array of a highly potent pharmaceuticals that can selectively cause apoptosis in various cancer cells and to synthesize click chemistry components to be used in ... -
Solvatochromic pyrogallarenes and pyrogallarene crystals
(University of Missouri--Columbia, 2018)Pyrogallarenes have the ability to self-assemble into a variety of structures. Crystal forms ranging from bilayers to dimers and hexamers have been isolated. One unique cocrystal, PgC[subscript 3]-(CH[subscript 3])[subscript ... -
Isotope harvesting from the beam dump cooling loop at the facility for rare isotope beams (FRIB)
(University of Missouri--Columbia, 2018)Isotope harvesting from the beam dump cooling loop of the Facility for Rare Isotope Beams (FRIB) offers usable quantities of many isotopes unavailable anywhere else in the world. Many of these co-produced isotopes are of ... -
Deep eutectic solvents : investigation of solvent structure and its applications
(University of Missouri--Columbia, 2017)[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Deep eutectic solvents (DESs) represent an alternative class of ionic fluids closely resembling room-temperature ionic liquids (RTILs), they are ... -
Synthesis and Reactivity of 1,2-Bis(di-iso-propylphosphino)benzene Nickel Complexes: A Study of Catalytic CO2-Ethylene Coupling [Datasets]
(2018)Single crystal X-ray diffraction photographs and data reduction output files in proprietary format, collected on a Bruker D8 Venture diffractometer with a Photon 100 detector using the Apex3 software suite. -
Structural basis of stability of human immunodeficiency virus type 1 (HIV-1) capsid
(University of Missouri--Columbia, 2017)Human immunodeficiency virus type 1 (HIV-1) is the etiologic agent of acquired immunodeficiency syndrome (AIDS). Since its discovery in early 1980, many advances have been made in the prevention and management of HIV/AIDS. ... -
Crossed-beam chemical reaction dynamics probed with universal and state resolved ion imaging
(University of Missouri--Columbia, 2018) -
Finite element analysis for the insertion process of the press-fitted total hip arthroplasty
(University of Missouri--Columbia, 2018)[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] There are more than 300,000 total hip arthroplasty (THA) surgeries performed every year in the United States. Press-fitted artificial hip joints are ... -
The synthesis of a fluorescent bioconjugation agent
(University of Missouri--Columbia, 2018)[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Bioconjugation linkers are used covalently link two molecules, where at least one is a large biomolecule for uses such as tracking cellular function, ... -
Synthesis and reactivity of actinide phosphorano stabilized carbene and phosphido complexes
(University of Missouri--Columbia, 2018)Nuclear power plants have been operated in the United States for over 60 years, generating over 800 terawatt-hours of energy per year. However, there is still no reliable process to recycle the spent nuclear fuel. This ... -
Radionuclide production and separation techniques for radiopharmaceutical development and nuclear waste processing
(University of Missouri--Columbia, 2018)With increasing cancer incident rates and advancements in nuclear medicine, the demand for optimizing pathways to produce radionuclides or investigating new radionuclides that improve current diagnostic and therapeutic ... -
Sustainable chemical approaches to two-dimensional nanosheets and mesoporous platforms and catalysts
(University of Missouri--Columbia, 2017)[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Green Chemistry, also called as Sustainable Chemistry, envisions minimum hazard to improve the efficiency and performance of materials while designing ... -
Deep UV resonance Raman spectral properties of alpha helical membrane proteins
(University of Missouri--Columbia, 2017)Membrane protein function and structure determination is vital for pharmaceutical development and disease prevention. Despite the various methods of protein structure elucidation in use, a need still exists for techniques ... -
Exploring chemical reaction complexity : application to hydrogen combustion
(University of Missouri--Columbia, 2017)The aim of this research is to gain insight into hydrogen combustion as a prototype of complex chemistry via classical molecular dynamics (CMD) simulations given the presently available reactive force field, ReaxFF. We ... -
Preparation of polymeric boron-containing nanoparticles by emulsion polymerization for application in boron neutron capture therapy (BNCT)
(University of Missouri--Columbia, 2010)[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Boron neutron capture therapy (BNCT) is based on the nuclear capture reaction of isotope [superscript 10]B irradiated by low energy thermal neutron to ... -
Fluorescent chemosensors for the detection of biological amines
(University of Missouri--Columbia, 2014)Chemical sensing has become an important field for the study of bioanalytes and provides key information pertaining to disease pathogenesis, and the physiological mechanisms underlying cellular processes. Discussed herein ... -
Deep ultraviolet resonance Raman spectroscopy as a tool for biomolecule analysis
(University of Missouri--Columbia, 2017)Cholesterol is a major component of membranes, reducing their fluidity at higher concentrations. The UV Raman vibrational mode of the carbon-carbon double bond in cholesterol occurs at 1675 cm-1 is strongly resonance ...