• Ammonia elimination from protonated nucleobases 

    Yang, Shuo (University of Missouri--Columbia, 2007)
    The dediazoniations of the diazonium ion 1 of 4-aminopyrimidine and of the tautomeric cytosinediazonium ions 2 and 3 are facile and result in the formations of cations 4, 5, and 6. The pyrimidine ring-opening of 4, 5 and ...
  • The effects of structural modifications on sigma receptor binding 

    Xu, Rong, 1977- (University of Missouri--Columbia, 2007)
    The sigma receptor is a unique receptor family that has two subtypes: sigma1 and sigma2. Sigma1 receptors are involved in several physiological functions such as psychosis and depression. Sigma2 receptors are expressed in ...
  • Ligands for the sigma receptor and the mu-opioid receptor 

    Lu, Yu, 1983- (University of Missouri--Columbia, 2007)
    The sigma receptor is a unique receptor family with two subtypes: sigma-1 and sigma-2. In order to conduct structure-activity relationship studies (SAR), a series of specific 1-phenylpropyl-4-benzylpiperidine and ...
  • Molecular dynamics simulations of pressure shocks in liquid phase nitromethane 

    McNatt, Michael David, 1972- (University of Missouri--Columbia, 2007)
    The dynamic energy transfer processes present in liquid nitromethane (NM) under pressure shock loading conditions have been investigated by nonequilibrium molecular dynamics methods using a previously developed, fully ...
  • Novel chemical mechanisms of DNA damage by natural products 

    Dutta, Sanjay (University of Missouri--Columbia, 2007)
    Leinamycin is a structurally novel natural product isolated from the streptomyces with potent ant tumor and antibiotic activity. In a thiol rich environment, leinamycin generates an episulfonium ion that alkylates ...
  • Organo nickel and platinum chemistry at the edge of corannulene 

    Lee, Han Baek, 1974- (University of Missouri--Columbia, 2007)
    The reaction of corannulene bromide with "NiL₂" or "PtL₂" (L = PEt₃ or PMe₃) gives corannulenyl complexes of [sigma] - bonded nickel and platinum, cis- and trans-MBrL₂R (M = Ni, Pt, R = C₂₀H₉, C₂₀H₆Br₃). Mono and dinuclear ...
  • Structure and synthesis of four supramolecular structures involving Cu(I) and 4,7-phenanthroline 

    Huesgen, Brian, 1978- (University of Missouri--Columbia, 2007)
    The design and synthesis of supramolecular species with discrete geometric shapes has been an area of much interest and research in recent years. Three isolated species of square shaped molecules and one infinite network ...
  • Studies on the nucleophilic substitution reactions of a dimeric cyclopentadienone 

    Balan, Gayatri (University of Missouri--Columbia, 2007)
    Nucleophilic substitution reactions of 3,5-Dibromo-3a,4,7,7a-tetrahydro-4,7-methano-indene-1,8-dione (48) have been studied. Amines, thiols and alcohols have been employed, with considerable success, as nucleophilic agents ...