• Advances in aptamer evolution and engineering 

    Alam, Khalid Kamal (University of Missouri--Columbia, 2016)
    Aptamers are single-stranded nucleic acids that fold into unique three-dimensional shapes that allow them to bind with high affinity and specificity to targets of interest. They are selected through the process of in vitro ...
  • The minimal primary structures of RNA aptamers selected to bind HIV-1 reverse transcriptase 

    Franken, Joshua D., 1983- (University of Missouri--Columbia, 2010)
    Human Immunodeficiency Virus (HIV) reverse transcriptase (RT) is the most common molecular target of current HIV treatments. Oligonucleotide aptamers bind and inhibit the RNA- and DNA-dependent polymerization activities ...