Browsing Department of Biochemistry (MU) by Thesis Advisor "Hannink, Mark, 1958-"
Now showing items 1-3 of 3
-
Characterization of PGAM5
(University of Missouri--Columbia, 2013)Programmed cell death (PCD) is a naturally occurring event that is highly regulated and required for normal development. The protein phosphoglycerate mutase 5 (PGAM5) has been implicated in apoptosis, necrosis, and autophagy ... -
Crystal structure of the kelch domain of human keap1
(University of Missouri--Columbia, 2005)[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Nrf2-Keap1 signal transduction pathway senses oxidative stress and protects eukaryotic cells against oxidative damage and cancer. The transcription ... -
Regulation of Nrf2 by a keap1-dependent E3 ubiquitin ligase
(University of Missouri--Columbia, 2007)Oxidative damage to biological macromolecules has been implicated in diverse pathophysiological processes, including cancer, neurodegeneration, aging and cardiovascular disease. The Nrf2 transcription factor regulates ...