Browsing Biochemistry electronic theses and dissertations (MU) by Thesis Semester "2008 Fall"
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Discovery of epitopes governing MMP-12 specificity for fibrillar substrates: BINDSIght, a method for determining specific sites of substrate surface interactions (University of Missouri--Columbia, 2008)What determines MMP-12 elastase activity? We have found that the fibrillar substrate specificity of MMP-12 involves surfaces ranging beyond the intensively studied active site cleft and S1' pocket. This was achieved by ...