Browsing Division of Animal Sciences (MU) by Thesis Advisor "Sutovsky, Peter"
Now showing items 1-8 of 8
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Arachidonate 15-lipoxygenase and ubiquitin as potential fertility markers in boars
(University of Missouri--Columbia, 2004)[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] This study was performed to determine whether using high power microscopic analysis and two putative biochemical fertility markers, 15-lipoxygenase ... -
Autophagy and ubiquitin-proteasome system during post-fertilization sperm mitophagy
(University of Missouri--Columbia, 2016)[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Maternal inheritance of mitochondria and mitochondrial DNA (mtDNA) is a universal principle in developmental biology. Mammalian sperm-borne mitochondria ... -
Characterization of a transgenic pig model carrying green fluorescent proteasomes
(University of Missouri--Columbia, 2013)The Ubiquitin Proteasome System (UPS) participates in many biological processes involving substrate-specific proteolysis, and can be linked to various pathologies and genetic diseases. Unfortunately, little is known about ... -
Discovery and phenotyping of the determinants and receptors of post-fertilization sperm mitophagy
(University of Missouri--Columbia, 2023)[EMBARGOED UNTIL 12/1/2024] This thesis is concerned with two important aspects of sperm physiology -- mitochondrial health prior to fertilization and mitochondrial inheritance after fertilization. The factors and mechanisms ... -
Involvement of mitochondrial transcription factor A (TFAM) in porcine gametogenesis and preimplantation embryo development
(University of Missouri--Columbia, 2007)Mitochondrial Transcription Factor A (TFAM) is responsible for maintenance and transcriptional control of mitochondrial DNA (mtDNA). TFAM knockout is embryolethal. We have studied the expression and distribution of TFAM ... -
Negative biomarkers of sperm quality and male fertility
(University of Missouri--Columbia, 2011)Semen evaluation via traditional light microscopy provides information about sperm motility and basic morphology but has a limited ability to predict reproductive performance in an assisted reproduction setting. In-depth ... -
Proteasomal proteoloysis during porcine fertilization
(University of Missouri--Columbia, 2012)Protein degradation is essential for maintaining a healthy cellular state. One such protein degradation pathway is the Ubiquitin Proteasome System (UPS) that consists of a small chaperone protein ubiquitin, a proteolytic ... -
Zinc ion fluxes on the pathway to mammalian sperm fertilization competency
(University of Missouri--Columbia, 2019)For decades, the role of the divalent ion calcium was the focus of understanding mechanisms leading to sperm fertilization competency and management of semen storage. Little focus has been placed on other divalent ions, ...