Search
Now showing items 1-8 of 8
Determination of allelic expression of H19 in pre- and peri-implantation mouse embryos
(University of Missouri--Columbia, 2013)
H19 is a maternally-expressed imprinted non-coding RNA with tumor suppressor activity. H19 is located in an imprinted cluster which contains the paternally-expressed fetal growth factor Igf2. Monoallelic expression of H19 ...
Effects of the use of assisted reproduction and high caloric diet consumption on body weight and cardiovascular health of juvenile mouse offspring
(University of Missouri--Columbia, 2013)
Maternal obesity and the use of assisted reproductive technologies (ART) are two suboptimal developmental environments that can lead to offspring obesity and cardiovascular disease. We hypothesized that these environments ...
Establishment of a phenotypical model of adverse outcomes associated with assisted reproductive technologies
(University of Missouri--Columbia, 2011)
Beckwith-Wiedemann syndrome (BWS) is a loss-of-imprinting pediatric overgrowth syndrome. BWS is speculated to occur primarily as the result of the misregulation of imprinted genes associated with two clusters on chromosome ...
Size-dependent acquisition of global DNA methylation in oocytes is altered by hormonal stimulation
(University of Missouri--Columbia, 2011)
Administration of exogenous gonadotropins (superovulation) is used to increase the number of mature oocytes to circumvent the inefficiencies of the subsequent assisted reproductive technologies procedures. Some evidence ...
Molecular characterization of a congenital overgrowth syndrome induced by assisted reproduction
(University of Missouri--Columbia, 2017)
Beckwith-Wiedemann syndrome (BWS) is a congenital overgrowth condition with increased likelihood to develop childhood tumors. Children conceived with the use of assisted reproductive technologies (ART) have an increased ...
Altered microrna expression profiles in bovine fetuses with an assisted reproduction-induced congenital overgrowth syndrome
(University of Missouri--Columbia, 2018)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Assisted reproductive technologies (ART) refer to a series of fertility treatments used to conceive offspring. ART is used worldwide in humans for ...
The effects of aging and fsh on the epigenome of the mouse oocyte
(University of Missouri--Columbia, 2015)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] With aging, females experience a natural decline in their reproductive success, partly due to a decline in the quality of the oocyte (ovum/egg). In ...
Large offspring syndrome, a bovine model for the human loss-of-imprinting overgrowth syndrome Beckwith-Wiedemann
(University of Missouri--Columbia, 2013)
Beckwith-Wiedemann syndrome (BWS) is a human loss-of-imprinting syndrome primarily characterized by macrosomia, macroglossia, and abdominal wall defects. BWS has been associated with misregulation of two clusters of imprinted ...