Browsing Department of Statistics (MU) by Title "Adaptive optimal design with application to a two drug combination trial based on efficiency-toxicity response"
Now showing items 1-1 of 1
-
Adaptive optimal design with application to a two drug combination trial based on efficiency-toxicity response
(University of Missouri--Columbia, 2009)[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] The first part of this dissertation develops an adaptive optimal design for dose-finding with combination therapies that accounts for both efficacy ...