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Rapid detection and characterization of mycobacteria using microchannel electrical impedance spectroscopy
(University of Missouri--Columbia, 2017)
The presence of virulent, pathogenic bacteria in our body, food, water and other consumables is harmful and causes enormous economic and personal losses. Here we will be looking at developing a platform technology that can ...
The role of Pre-B-cell colony-enhancing factor in neuronal death after ischemia and motor dysfunction
(University of Missouri--Columbia, 2016)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Pre-B-cell colony-enhancing factor (PBEF) is the rate-limiting enzyme in the salvage pathway of mammalian nicotinamide adenine dinucleotide (NAD+) ...
Peptide nanoconjugates for tissue diagnostics and molecular imaging
(University of Missouri--Columbia, 2016)
The rise of targeted therapy in cancer treatment has created a strong need for characterization of a patient's tumor before receiving treatment. Many effective cancer drugs are now being targeted to specific proteins present ...
Quantification of cell attachment on different materials as candidate electrodes for measurement of quantal exocytosis
(University of Missouri--Columbia, 2008)
A high throughput lab-on-a-chip device is being developed for single cell capture for the purpose of high time resolution quantal exocytosis measurement with high probability of cell docking. This device makes use of DLC ...
CPLA2: key enzyme for astroctytic cell membrane phase property change induced by abeta
(University of Missouri--Columbia, 2007)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] The interaction of amyloid beta peptide (A[beta]) and cell membrane is believed to be the basis of its biological function including its toxicity to ...
Properties of extruded white corn flour - high amylose corn starch puffs
(University of Missouri--Columbia, 2008)
This study was conducted to determine the effect of high-amylose corn starch in corn puffs on the extrusion parameters, product and textural properties and the glass transition temperature. The data was analyzed in a ...
Aptamer encoded nanopores as single molecule sensors
(University of Missouri--Columbia, 2008)
We have created a low noise, calibrated, molecular-scaled pore. The nanopore is formed either by micro-forge polishing or external penetration of the nanocavity sealed in the pipette terminal. The nanopore fabrication is ...
Development of a biosensor for the detection of Helicobacter hepaticus utilizing multi-functioning immobilization platforms
(University of Missouri--Columbia, 2010)
Optical biosensor development is a process involving the careful selection of the material for the immobilization platform, design of the detection mechanism and integration with optical and electronic equipment. The ability ...
Investigative study of long-term packaging effects and donor characteristics on acellular dermis scaffolds
(University of Missouri--Columbia, 2008)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Acellular tissue sources have become progressively popular for a variety of tissue engineering and medical applications, such as soft tissue augmentation, ...
Applications of gel electrophoresis in quantum dot conjugates' separation and purification
(University of Missouri--Columbia, 2009)
The objectives of this study were to build Quantum dot (QD) crosslinker complexes for antibody conjugation usage, to purify QD crosslinker complexes by gel electrophoresis and to check the biological functionalities of ...
Development of a post-traumatic osteoarthritis model to evaluate the effects of impact velocity and maximum strain on articular cartilage cell viability, matrix biomarkers, and material properties
(University of Missouri--Columbia, 2009)
Post-traumatic osteoarthritis (PTOA) is a very painful and debilitating disease that is associated with mechanical injury to articular cartilage, yet the severity of trauma required to induce it is unknown. The objective ...
Geographic information systems used for precision agriculture : knowledge and use by agriculture students at the University of Missouri (MU)
(University of Missouri--Columbia, 2010)
The use of GIS in PA technology helps manage the information intensive environment in production agriculture by intertwining site-specific (within field) management with computer software modeling for analyses and ...
Development of novel bionanocomposite scaffolds
(University of Missouri--Columbia, 2008)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] The development of three novel bionanocomposite scaffolds is presented in this dissertation. These scaffold materials are comprised of amine-functionalized ...
Development and applications of label-free optofluidic ring resonator biosensor
(University of Missouri--Columbia, 2009)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] This dissertation presents the development and applications of label-free optofluidic ring resonator (OFRR) sensor platform. The OFRR sensor naturally ...
Functional study of Kcv potassium channel through manipultion [sic] of individual subunits
(University of Missouri--Columbia, 2010)
Potassium channels make up a ubiquitous, physiologically essential class of integral membrane proteins. Many K+ channels contain four identical symmetrically associated subunits. To explore the role of an individual subunit ...
Manure management using precision agriculture
(University of Missouri--Columbia, 2010)
The overall purpose of this project was to develop and implement a manure application record system that was solely based on Global Positioning Systems (GPS). This system will have the ability to provide steering and ...
A fiber-optic confocal scanner for scattering tissue
(University of Missouri--Columbia, 2009)
Confocal microscopy has become an important diagnostic tool in examining scattering tissues. The high resolution of confocal microscopy and its optical sectioning capabilities lend itself as a desirable modality in examining ...
Ion-selective electrodes for simultaneous real-time analysis for soil macronutrients
(University of Missouri--Columbia, 2006)
Automated sensing of soil macronutrients (i.e., N, P, and K) would allow more efficient mapping of soil nutrient variability for variable-rate nutrient management. This study reports on the development of a sensor array ...
Photoacoustic detection of metastatic melanoma in the human circulatory system
(University of Missouri--Columbia, 2006)
Detection of disseminating tumor cells can function as an early warning system, alerting the metastatic spread or recurrence of the disease. Early detection of such cells can result in preventative treatment of the disease ...
Detection of cold flow properties of diesel and biodiesel fuel using optical sensor
(University of Missouri--Columbia, 2006)
Identification of cloud point for biodiesel fuel can be used to optimize the performance of biodiesel fueled vehicles in cold weather. Cloud point is the temperature at which the smallest cluster of wax crystal is observed ...