RSS 1.0Biological Engineering electronic theses and dissertations - Engineering (MU)
The items in this collection are the theses and dissertations written by students of the Department of Biological Engineering. Some items may be viewed only by members of the University of Missouri System and/or University of Missouri-Columbia. Click on one of the browse buttons above for a complete listing of the works.
Items in MOspace are protected by copyright, with all rights reserved, unless otherwise indicated.
Recent Submissions
-
Four-limb IMU sensors for canine gait analysis
(University of Missouri--Columbia, 2019)Canine models of human musculoskeletal diseases, such as Duchenne muscular dystrophy (DMD), are important translational animal models for developing therapies. Musculoskeletal diseases alter gait performance, and gait ... -
The impact of adverse maternal environments on resistance artery function and mechanical characteristics in offspring
(University of Missouri--Columbia, 2020)Cardiovascular disease is one of the leading causes of death worldwide. Maternal obesity, gestational diabetes mellitus (GMD) and assisted reproductive technologies (ART) have been associated with cardiovascular deficiencies ... -
Targeted therapeutics for non small cell lung carcinoma
(University of Missouri--Columbia, 2019)[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] "Lung carcinoma, also known as lung cancer, is a malignant tumor of lungs characterized by uncontrolled call growth in lung tissue. Tobacco smoking ... -
Use of geographic information systems and remote sensing as automated tool for variable rate irrigation prescriptions
(University of Missouri--Columbia, 2019)[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Economic as well as water shortage pressure on agricultural use of water has placed added emphasis on efficient irrigation management. Center pivot ... -
Multi-scale self-assembly of nanoenergetic materials utilizing functionalized graphene
(University of Missouri--Columbia, 2020)The work described here-in focuses on the synthesis and characterization of novel nanoenergetic materials and is driven by overcoming the disadvantages of traditional nanoenergetic composites, improving the energetic ... -
Imaging structural and mechanical properties of articular cartilage using optical polarization tractography
(University of Missouri--Columbia, 2019)[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Osteoarthritis (OA) is an extremely common joint disease, which affects more than one-third of all adults in the USA. Although the entire joint ... -
Engineering target nanomaterials for stable and efficient delivery of siRNA
(University of Missouri--Columbia, 2019)[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI--COLUMBIA AT REQUEST OF AUTHOR.] Lung cancer has the highest cancer-related mortality rate in the United States. The most common form of lung cancer is non-small cell lung ... -
Design and synthesis of targeted NIR fluorescent nanoparticles for bio-imaging
(University of Missouri--Columbia, 2019)[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI--COLUMBIA AT REQUEST OF AUTHOR.] Breast cancer is the second most common cancer, and the chance that a woman will die from breast cancer is 2.6%. One in 8 women develop ... -
Prediction of knee loading in native knee and total knee arthroplasty : a forward dynamics computational study
(University of Missouri--Columbia, 2019)"The goal of this dissertation is to develop a musculoskeletal model and corroborate model predictions to experimentally measured in vivo knee contact forces, in order to study the biomechanical consequences of two different ... -
The design of fluorescence correlation spectroscopy for single molecule techniques
(University of Missouri--Columbia, 2019)The ribosome is responsible for protein synthesis--a critical process in creating essential proteins for cell survival. Though bulk techniques yield valuable results about the structure of the ribosome, bulk techniques are ... -
Direct from sample phenotypic antibiotic susceptibility testing
(University of Missouri--Columbia, 2018)To transition from broad-spectrum antibiotic therapy to a more effective "targeted" therapy, i.e. in order to determine whether the infecting strain is resistant or susceptible to individual candidate antibiotics, clinicians ... -
Direct-from-sputum rapid phenotypic drug susceptibility test for mycobacteria
(University of Missouri--Columbia, 2018)The spread of multi-drug resistant tuberculosis (MDR-TB) is a leading global public-health challenge. Because not all biological-mechanisms of resistance are known, culture-based (phenotypic) drug-susceptibility testing ... -
Porous silicates for applications in smart water treatment systems and antimicrobial biomedical coatings
(University of Missouri--Columbia, 2018)[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Porous silicates, particularly ordered ones, may find novel and wide-ranging applications in the bioengineering arena in the near future. For instance, ... -
Climate and land use effects on hydrologic processes and water allocation in a primarily rain-fed, agricultural watershed
(University of Missouri--Columbia, 2018)[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] There is a need to raise our understanding of the impact of climate variability and change on hydrologic processes at the watershed scale. This is ... -
Climate change impacts on hydrologic components and occurrence of drought in an agricultural watershed
(University of Missouri--Columbia, 2018)The study on potential acceleration of future hydrologic cycle due to change in precipitation and increase in temperature are essential for managing natural resources and setting policy. The impact of future climate change ... -
Green solvent-enabled biomass conversion for renewable chemicals and lignin upgrading
(University of Missouri--Columbia, 2018)Lignocellulosic biomass, which is mainly composed of cellulose, hemicellulose, and lignin, is a promising feedstock for producing renewable chemicals and fuels. To make lignocellulosic biomass-based refinery (biorefinery) ... -
Methods of imaging articular cartilage under shear
(University of Missouri--Columbia, 2019)Characterizing both the structure of articular cartilage, and its biomechanical properties is key to gaining a full understanding of how the tissue functions. Articular cartilage is an inhomogeneous tissue with a depth ... -
Accurate DNA microsatellite and microRNA detection with a biological nanopore
(University of Missouri--Columbia, 2019)[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI--COLUMBIA AT REQUEST OF AUTHOR.] Nanopore-based detection has been used in many genetic, epigenetic, proteomic, and bio-mechanism studies. In this report, we introduced two ... -
Automatic four-limb IMU gait analysis in the canine DMD model
(University of Missouri--Columbia, 2018)[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Gait analysis is valuable for studying neuromuscular and skeletal diseases. Wearable motion sensors or inertial measurement units (IMUs) possess ... -
Automated detection of amperometric spikes resulting from quantal exocytosis and estimation of spike and pre-spike foot signal parameters
(University of Missouri--Columbia, 2018)Electrochemical microelectrodes can detect single-vesicle release events as "spikes" of amperometric current. We developed a template based "matched-filter" approach that performs least squares fit of a library of templates ...