Browsing Biological Engineering electronic theses and dissertations - Engineering (MU) by Thesis Advisor "Sengupta, Shramik"
Now showing items 1-7 of 7
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Direct from sample phenotypic antibiotic susceptibility testing
(University of Missouri--Columbia, 2018)To transition from broad-spectrum antibiotic therapy to a more effective "targeted" therapy, i.e. in order to determine whether the infecting strain is resistant or susceptible to individual candidate antibiotics, clinicians ... -
Direct-from-sputum rapid phenotypic drug susceptibility test for mycobacteria
(University of Missouri--Columbia, 2018)The spread of multi-drug resistant tuberculosis (MDR-TB) is a leading global public-health challenge. Because not all biological-mechanisms of resistance are known, culture-based (phenotypic) drug-susceptibility testing ... -
Microrna detection by surface plasmon resonance
(University of Missouri--Columbia, 2014)[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Lung cancer is the leading cause of cancer death in the world out of over 100 different known human cancers. Therefore there is a need for better ... -
Multi-frequency electrical impedance method for detection of viable micro-organisms, their quantification and their characterization
(University of Missouri--Columbia, 2013)Despite advances in DNA based technologies and molecular methods, there are still several drawbacks to these methods and hence, there is a need for development of a new technology for microbial detection and quantification. ... -
Rapid detection and characterization of mycobacteria using microchannel electrical impedance spectroscopy
(University of Missouri--Columbia, 2017)The presence of virulent, pathogenic bacteria in our body, food, water and other consumables is harmful and causes enormous economic and personal losses. Here we will be looking at developing a platform technology that can ... -
Rapid estimation of antibiotic efficacy of low bacterial inoculums using multi-frequency impedance measurements
(University of Missouri--Columbia, 2015)Background: In order to obtain Minimum Inhibitory Concentrations (MICs), antibiotics are, by convention, tested against turbidometrically standard suspensions containing [about]5x105 CFU/ml of bacteria. This not only fails ... -
Rapid isolation of target bacteria from complex matrices
(University of Missouri--Columbia, 2010)The long term goal of the research effort in our group was to develop a new rapid diagnostic process for sepsis. The specific project described in this work aims to obtain these "pure" isolates of the infectious bacteria ...