Browsing Molecular Microbiology and Immunology electronic theses and dissertations (MU) by Thesis Advisor "Hahm, Bumsuk"
Now showing items 1-4 of 4
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Influenza virus strategies to regulate S1P-metabolizing enzymes and evade host innate immunity for robust viral replication
(University of Missouri--Columbia, 2021)Viral infection is a complex network of interactions involving the host defending itself against the virus and the virus attempting to subdue host defenses and utilize the cellular machinery to promote its replication. ... -
The role of sphingosine 1-phosphatemetabolizing enzymes in host defense to RNA virus infections
(University of Missouri--Columbia, 2016)[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Viruses are intracellular parasites that rely on the host cell machinery to effectively replicate themselves and spread within the host to cause ... -
The role of sphingosine kinase in influenza virus mediated inflammasome activitation
(University of Missouri--Columbia, 2013)[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Influenza viruses continue to pose a grave burden on the global health and economy. Dysregulated innate immune system can lead to rapid infiltration ... -
Virus interactions with the sphingolipid network : sphingosine kinase 2 in immunosuppression, immunopathology, and viral propagation
(University of Missouri--Columbia, 2020)Sphingosine 1-phosphate (S1P) is a bioactive lipid molecule known to regulate diverse cellular functions. S1P is metabolized by the sphingosine kinases (SphK) and S1P lyase (SPL). However, little is known about the role ...