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Three mutations that cause fifferent [i.e. different] forms of canine neuronal ceroid lipofuscinosis
(University of Missouri--Columbia, 2006)
Neuronal ceroid-lipofuscinosis (NCL), also known as Battens disease, is really a group of inherited neurodegenerative diseases. A common feature of the ceroid lipofuscinoses is the deposition of autofluorescent cytoplasmic ...
Role of the intermediate-conductance Ca²⁺-activated K⁺ channel (K[ca]3.1) in coronary smooth muscle cell phenotypic modulation
(University of Missouri--Columbia, 2007)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Smooth muscle cell phenotypic modulation is characterized by suppression of smooth muscle specific marker gene expression, migration, and proliferation ...
Mechanisms regulating skeletal muscle satellite cell cycle progression
(University of Missouri--Columbia, 2006)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Skeletal muscle fibers are multinucleated with each myonucleus capable of governing a finite cytoplasmic volume. In healthy skeletal muscle, myonuclear ...
Gold nanoparticle-biomolecule conjugates : synthesis, properties, cellular interactions and cytotoxicity studies
(University of Missouri--Columbia, 2008)
This research focuses on conjugation of two major biomolecules i.e., Bombesin and Annexin V, to AuNps and studying their target specificity. The target specificity of AuNps coated with Bombesin, a GRP receptor specific ...
Prevalence of Staphylococcus aureus and MRSA carriage in three populations
(University of Missouri--Columbia, 2008)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] A higher prevalence of methicillin-resistant Staphylococcus aureus (MRSA) colonization has been reported in healthcare workers than in non-healthcare ...
Upregulation of COX-2 protein expression in porcine macula densa with L-NAME treatment
(University of Missouri--Columbia, 2008)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] COX-2 inhibitors are newly developed drugs which are widely used for controlling pain and inflammation. Blocking this enzyme impedes the production ...
Specific neuronal phenotypes within the rostral ventrolateral medulla following cardiovascular deconditioning in rats
(University of Missouri--Columbia, 2008)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Humans exposed to prolonged periods of bed rest or spaceflight undergo multiple cardiovascular adaptations including a predisposition for orthostatic ...
Inhibition of progestin-induced VEGF in mammary cancer by curcumin and 2-methoxy estradiol and their potential role as anti-angiogenic & chemopreventive compounds
(University of Missouri--Columbia, 2009)
Estrogen/Progestin combined hormone replacement therapy (HRT) is commonly prescribed to alleviate the symptoms of menopause in women. Combination HRT however is associated with an increased risk of breast cancer, an effect ...
Analysis of coffin and shoulder joint lameness with an inertial sensor-based system : impact versus pushoff
(University of Missouri--Columbia, 2012)
Reason for performing the study: An inertial sensor-based system (Lameness Locator[copyright] [LL]) can help veterinarians detect mild lameness. It would be beneficial if this tool could also be used to distinguish lamenesses ...
The antiendotoxin effects of polymyxin B in a feline model of endotoxemia
(University of Missouri--Columbia, 2010)
Introduction: Directed, effective therapies for feline sepsis are needed to reduce the high morbidity and mortality associated with this disease. Materials and Methods: We investigated the anti-endotoxin effects of PMB in ...
A missense mutation in Atf2 in standard poodles with fatal neonatal encephalopathy
(University of Missouri--Columbia, 2007)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Neonatal encephalopathy with seizures (NEWS) is a previously undescribed autosomal recessive disease in Standard Poodles. Affected puppies are small ...
Fgf2-stimulated proliferation is lower in muscle precursor cells from old rats
(University of Missouri--Columbia, 2009)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] In aged skeletal muscle, impairments in the regrowth and regeneration may be explained by a decreased responsiveness of muscle precursor cells (MPCs), ...
In vitro evaluation of veterinary and human suture anchors in metaphyseal bone of the canine tibia
(University of Missouri--Columbia, 2006)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Suture anchors, also called bone or tissue anchors, provide orthopedic surgeons a mechanism for secure fixation of soft tissues to bone. A human system ...
Characterization of the humoral immune response to a commercial staphylococcus aureus mastitis vaccine
(University of Missouri--Columbia, 2006)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] The objective of this thesis was to test the hypothesis that a commercial vaccine for bovine S. aureus mastitis fails to induce a humoral immune response ...
Characterization of the alignment of the canine pelvic limb
(University of Missouri--Columbia, 2009)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Angular limb deformities are common place in the canine. Until recently, repair of deformities was based upon crude radiographic measures of bone ...
Estradiol regulates multiple tetrodotoxin-sensitive sodium currents in gonadotropin releasing hormone neurons: implications for cellular regulation of reproduction
(University of Missouri--Columbia, 2009)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] The gonadotropin releasing hormone (GnRH) neuron is the pivotal control center in a tightly regulated reproductive axis. Estradiol typically has a ...
Estrogen receptor [alpha] and [beta] knock-out effects on skeletal muscle in mature female and male mice, and aromatase knock-out effects on skeletal muscle in mature male mice
(University of Missouri--Columbia, 2007)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Estrogen regulates skeletal muscle mass and function in female. Estrogen may influence skeletal muscle mass and function during development in males ...
Comparative imaging of canine shoulder osteochondrosis lesions
(University of Missouri--Columbia, 2010)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Over the last several years, papers have been published describing imaging techniques for the canine shoulder joint using both ultrasound and magnetic ...
Immunomodulators in feline asthma
(University of Missouri--Columbia, 2010)
Experimental asthma was induced in 10 cats using Bermuda grass allergen (BGA) and cats were randomly selected to receive either feG (1 mg/kg, PO) or saline for 2 weeks, followed by a 2 week washout period before receiving ...
Sympathetic control of the collateral circulation : effects of time post-occlusion and exercise training
(University of Missouri--Columbia, 2008)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] These studies evaluated the role of alpha-adrenergic receptors ([alpha]AR) and NPYergic receptors in the collateral circulation following acute and ...