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Immunomodulatory effects of opioids
(University of Missouri--Columbia, 2010)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Opioids have been shown to modulate the immune system in animal models by affecting both the acquired and innate arms of the immune system. Many of ...
Immunomodulators in feline asthma
(University of Missouri--Columbia, 2010)
Experimental asthma was induced in 10 cats using Bermuda grass allergen (BGA) and cats were randomly selected to receive either feG (1 mg/kg, PO) or saline for 2 weeks, followed by a 2 week washout period before receiving ...
Comparative imaging of canine shoulder osteochondrosis lesions
(University of Missouri--Columbia, 2010)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Over the last several years, papers have been published describing imaging techniques for the canine shoulder joint using both ultrasound and magnetic ...
Vascular maladaptations to chronic disease and physical inactivity
(University of Missouri--Columbia, 2010)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Physical inactivity due to increases in modern conveniences and access to cheap, high calorie foods have greatly contributed to the "obesity epidemic" ...
Interdisciplinary Approach to Examine the Effects of Lifestyle Modifications on Nonalcoholic Fatty Liver Disease
(2010)
A critical complication of the obesity epidemic experienced in Westernized societies is nonalcoholic fatty liver disease (NAFLD). NAFLD, fatty liver not due to alcohol consumption, is the most common chronic liver disease ...
Vascular actions of insulin in cardiometabolic disease : effects of metformin, physical activity, and intrinsic aerobic fitness
(University of Missouri--Columbia, 2013)
Insulin has important vascular and metabolic actions. The vascular effects of insulin typically account for as much as 40-50% of insulin-stimulated glucose disposal. However, the vascular reactivity to insulin is impaired ...
Neurons projecting to the paraventricular nucleus of the hypothalamus are activated and contribute to cardiorespiratory responses to systemic acute hypoxia
(University of Missouri--Columbia, 2013)
Activation of peripheral and central chemoreceptors contributes to homeostatic responses that maintain optimal blood gas levels, including oxygen and carbon dioxide. Brainstem neurons in the nTS and CVLM integrate and ...
The use of a lysostaphin fusion protein as a dry-cow treatment for chronic Staphylococcus aureua mastitis in dairy cattle
(University of Missouri--Columbia, 2013)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] This study evaluated the efficacy of a lysostaphin-fusion protein (Lyso-PTD) as a dry-cow therapy for the treatment of experimentally-induced chronic, ...
Parenteral fish oil effects on plasma non-esterified fatty acids and systemic cytokine concentrations in dogs immediately following ovariohysterectomy
(University of Missouri--Columbia, 2012)
An extreme systemic inflammatory response may be observed in dogs that experience severe accidental trauma, such as being struck by a car. The inflammatory response may be so extreme that it complicates treatment and causes ...
6-Thioguanine and zebularine globally demethylate a canine lyphoma cell line
(University of Missouri--Columbia, 2014)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Epigenetic modifications of chromatin, including methylation, histone modifications, and protein chaperoning, play a significant role in the biology ...
Canine pharmacodynamic assays: applications in immune-mediated disease
(University of Missouri--Columbia, 2013)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Immune-mediated diseases are commonly diagnosed in veterinary medicine and a high rate of mortality, expense and complications of immunosuppressive ...
Molecular epidemiology of tick-borne Anaplasmataceae among client-owned dogs in Missouri
(University of Missouri--Columbia, 2012)
Several tick-borne agents of zoonotic ehrlichiosis or anaplasmosis are endemic to Missouri. Dogs are susceptible to the same infections and tick vectors, but their roles as models, sentinels or reservoirs are undefined. ...
Targeting the myofibroblast : new strategies in managing equine corneal fibrosis
(University of Missouri--Columbia, 2014)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Corneal disease is a common cause of blindness in horses as a result of various causes including traumatic, autoimmune, neoplastic, or infectious ...
Comparison of an inertial sensor based system of lameness quantification to subjective lameness evaluation
(University of Missouri--Columbia, 2012)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Recently developed wireless inertial sensor systems provide a means to objectively detect lameness as a horse is trotted over natural footing. The ...
Double pelvic osteotomy for the treatment of hip dysplasia in dogs
(University of Missouri--Columbia, 2011)
Canine hip dysplasia (CHD) is the most common developmental orthopedic disease of dogs. Triple pelvic osteotomy (TPO) is a surgery that can be performed at 5 months of age, prior to the development of osteoarthritis. ...
Paradoxical dysuria among dogs with degenerative lumbosacral stenosis
(University of Missouri--Columbia, 2011)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Degenerative lumbosacral stenosis (DLSS) is a multifactorial condition affecting predominantly large breed dogs. The combination of stenosis and ...
Apigenin : chemopreventive and chemotherapeutic potential for progestin-dependent breast cancer
(University of Missouri--Columbia, 2012)
Use of estrogen-progestin hormone replacement therapy (HRT) has been linked to increased risk of breast cancer, an effect that has been attributed to the progestin component. Commonly available antiprogestins are associated ...
Cytauxzoon felis : an emerging feline pathogen and potential therapy
(University of Missouri--Columbia, 2011)
Cytauxzoon felis is a pathogenic hemoprotozoal parasite of Felidae. We were able to document, via both piroplasm detection and PCR analysis, a chronic carrier state in naturally infected captive bred tigers as well as ...
The effects of furosemide on ureteral diameter and attenuation using computed tomographic excretory urography in normal healthy dogs
(University of Missouri--Columbia, 2012)
A number of imaging techniques have been employed to try and diagnose ureteral disease, including ectopic ureters. CTEU has overcome those disadvantages and has become the imaging modality of choice for evaluating human ...
Acute and chronic adaptations to intermittent pnemuatic [sic] leg compressions
(University of Missouri--Columbia, 2011)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Few therapies exist that improve functional capacity and quality of life of patients with peripheral arterial disease (PAD). Despite the growing ...