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A missense mutation in Atf2 in standard poodles with fatal neonatal encephalopathy
(University of Missouri--Columbia, 2007)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Neonatal encephalopathy with seizures (NEWS) is a previously undescribed autosomal recessive disease in Standard Poodles. Affected puppies are small ...
Mechanisms regulating skeletal muscle satellite cell cycle progression
(University of Missouri--Columbia, 2006)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Skeletal muscle fibers are multinucleated with each myonucleus capable of governing a finite cytoplasmic volume. In healthy skeletal muscle, myonuclear ...
Role of the intermediate-conductance Ca²⁺-activated K⁺ channel (K[ca]3.1) in coronary smooth muscle cell phenotypic modulation
(University of Missouri--Columbia, 2007)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Smooth muscle cell phenotypic modulation is characterized by suppression of smooth muscle specific marker gene expression, migration, and proliferation ...
In vitro evaluation of veterinary and human suture anchors in metaphyseal bone of the canine tibia
(University of Missouri--Columbia, 2006)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Suture anchors, also called bone or tissue anchors, provide orthopedic surgeons a mechanism for secure fixation of soft tissues to bone. A human system ...
Characterization of the humoral immune response to a commercial staphylococcus aureus mastitis vaccine
(University of Missouri--Columbia, 2006)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] The objective of this thesis was to test the hypothesis that a commercial vaccine for bovine S. aureus mastitis fails to induce a humoral immune response ...
Fgf2-stimulated proliferation is lower in muscle precursor cells from old rats
(University of Missouri--Columbia, 2009)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] In aged skeletal muscle, impairments in the regrowth and regeneration may be explained by a decreased responsiveness of muscle precursor cells (MPCs), ...
The effect of free fatty acids on endothelial cells
(University of Missouri--Columbia, 2005)
The purpose of this thesis was to determine if specific components of oxidized low density lipoprotein (OxLDL) molecules e.g. oxidized polyunsaturated fatty acids (PUFAs), or saturated free fatty acids (FFA) are alone ...
Characterization of the alignment of the canine pelvic limb
(University of Missouri--Columbia, 2009)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Angular limb deformities are common place in the canine. Until recently, repair of deformities was based upon crude radiographic measures of bone ...
Estradiol regulates multiple tetrodotoxin-sensitive sodium currents in gonadotropin releasing hormone neurons: implications for cellular regulation of reproduction
(University of Missouri--Columbia, 2009)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] The gonadotropin releasing hormone (GnRH) neuron is the pivotal control center in a tightly regulated reproductive axis. Estradiol typically has a ...
Three mutations that cause fifferent [i.e. different] forms of canine neuronal ceroid lipofuscinosis
(University of Missouri--Columbia, 2006)
Neuronal ceroid-lipofuscinosis (NCL), also known as Battens disease, is really a group of inherited neurodegenerative diseases. A common feature of the ceroid lipofuscinoses is the deposition of autofluorescent cytoplasmic ...
Modulation of the ACTH response to stress by IL-6, nitric oxide, diet and exercise
(University of Missouri--Columbia, 2006)
The release of ACTH from the anterior pituitary is one step in the activation of the Hypothalamic-Pituitary-Adrenal (HPA) axis. The HPA axis is activated in response to stress and the secretion of ACTH is under the control ...
Sensory integration during blood loss in conscious rabbits
(University of Missouri--Columbia, 2006)
Central nervous system integration of sensory inputs is critical for orchestrating physiological responses to stress. The focus of my doctoral research was investigating the physiological consequences of sensory stimulation ...
The cystic fibrosis transmembrane conductance regulator and acid-base transporters of the murine duodenum
(University of Missouri--Columbia, 2006)
The alkaline mucus barrier of the duodenum plays an important role in protecting the epithelium from acidic chyme entering from the stomach. Active HCO₃⁻ secretion involves the apical membrane activities of the cystic ...
Post-angioplasty restenosis : the effects of exercise training
(University of Missouri--Columbia, 2008)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Percutaneous transluminal coronary angioplasty (PTCA) stimulates vascular cell proliferation and migration resulting in restenosis of the revascularized ...
Sympathetic control of the collateral circulation : effects of time post-occlusion and exercise training
(University of Missouri--Columbia, 2008)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] These studies evaluated the role of alpha-adrenergic receptors ([alpha]AR) and NPYergic receptors in the collateral circulation following acute and ...
Prevalence of Staphylococcus aureus and MRSA carriage in three populations
(University of Missouri--Columbia, 2008)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] A higher prevalence of methicillin-resistant Staphylococcus aureus (MRSA) colonization has been reported in healthcare workers than in non-healthcare ...
Upregulation of COX-2 protein expression in porcine macula densa with L-NAME treatment
(University of Missouri--Columbia, 2008)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] COX-2 inhibitors are newly developed drugs which are widely used for controlling pain and inflammation. Blocking this enzyme impedes the production ...
Specific neuronal phenotypes within the rostral ventrolateral medulla following cardiovascular deconditioning in rats
(University of Missouri--Columbia, 2008)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Humans exposed to prolonged periods of bed rest or spaceflight undergo multiple cardiovascular adaptations including a predisposition for orthostatic ...
New Approaches for Estimating Risk from Exposure to Diethylstilbestrol
(The National Institute of Environmental Health Sciences, 1999)
A subgroup from a National Institute of Environmental Health Sciences, workshop concerned with characterizing the effects of endocrine disruptors on human health at environmental exposure levels considered the question, ...
Inhibition of progestin-induced VEGF in mammary cancer by curcumin and 2-methoxy estradiol and their potential role as anti-angiogenic & chemopreventive compounds
(University of Missouri--Columbia, 2009)
Estrogen/Progestin combined hormone replacement therapy (HRT) is commonly prescribed to alleviate the symptoms of menopause in women. Combination HRT however is associated with an increased risk of breast cancer, an effect ...