Browsing Medical Pharmacology and Physiology electronic theses and dissertations (MU) by Thesis Semester "2005 Spring"
Now showing items 1-5 of 5
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Effects of ischemic metabolites and chronic exercise on cardiac myocyte function
(University of Missouri--Columbia, 2005)During times of low blood flow (ischemia), concentrations of wastes increase in tissues, which can lead to decreased striated muscle contractile function. Acute cardiac contractile dysfunction during ischemia is likely ... -
Effects of treprostinil sodium in a monocrotaline-induced rat model of pulmonary hypertension
(University of Missouri--Columbia, 2005)Treprostinil is a prostacyclin analog currently used in the treatment of pulmonary hypertension. Although clinical studies show treprostinil to be a successful therapy for pulmonary hypertension, little information exists ... -
Metabolic and functional consequences of adenylate kinase deficiency in skeletal muscle
(University of Missouri--Columbia, 2005)[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] The primary function of skeletal muscle is to generate tension, and this ultimately occurs through ATP utilization. An increase in ADP and a depression ... -
P2Y[subscript 2] nucleotide receptor up-regulation and function in submandibular gland epithelium
(University of Missouri--Columbia, 2005)Sjögren's syndrome (SS) is an autoimmune disease that specifically targets exocrine glands, including salivary glands, and results in an impairment of secretory function. P2Y₂ nucleotide receptors for extracellular ATP ... -
Physical inactivity induced dysregulation of skeletal muscle and adipose tissue metabolism
(University of Missouri--Columbia, 2005)There has been a precipitous decline in the daily physical activity in humans that has been accompanied by an epidemic rise in the incidence of obesity and type II diabetes. This rapid decline in physical activity in humans ...