Browsing Medical Pharmacology and Physiology electronic theses and dissertations (MU) by Thesis Advisor "Hill, Michael A."
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Contribution of AT1R mechanoactivation to the arterial myogenic response and its regulation by RGS5 protein in skeletal muscle arterioles
(University of Missouri--Columbia, 2015)Although intracellular mechanisms underlying the arteriolar myogenic response have been well-defined, the mechanotransduction events transducing the mechanical stimulus remain unclear. Recently, ligand-independent activation ... -
Dendritic cells contribute to perivascular adipose tissue dysfunction in type 2 diabetes
(University of Missouri--Columbia, 2017)T2DM is a chronic disease characterized by low-grade inflammation in adipose tissue. Recent investigations have shown that a variety of immune cells can accumulate in adipose tissue contributing to the development of chronic ... -
The role of serum-glucocorticoid-regulated kinase (SGK1) in arterial reactivity
(University of Missouri--Columbia, 2023)[EMBARGOED UNTIL 8/1/2024] Objective: In the vascular system, aldosterone exerts several actions via genomic and non-genomic pathways through MR receptor-dependent/independent mechanisms. Aldosterone exerts its effect by ...