Browsing Medical Pharmacology and Physiology electronic theses and dissertations (MU) by Thesis Advisor "Shukla, Shivendra D."
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Alcohol induced histone acetylation mediated by histone acetyl transferase GCN5 in liver
(University of Missouri--Columbia, 2008)Although several mechanisms have identified for alcoholic liver disease, at present there are no precise mechanisms for liver injury. We have observed that surrogate alcohols increases histone H3 acetylation selectively ... -
Histone H3 phosphorylation and phosphoacetylation in the liver of rats treated in vivo with acute ethanol
(University of Missouri--Columbia, 2011)Epigenetic histone modification is emerging as a critical player in the cellular actions of ethanol. In this context, we administered ethanol intraperitoneally to rats, to mimic binge drinking in humans. A dose response ...