RSS 1.0Nutrition and Exercise Physiology electronic theses and dissertations (MU)
The items in this collection are the theses and dissertations written by students of the Department of Nutrition and Exercise Physiology. Some items may be viewed only by members of the University of Missouri System and/or University of Missouri-Columbia. Click on one of the browse buttons above for a complete listing of the works.
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Recent Submissions
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Estrogen in the nucleus accumbens : impacts on metabolism, wheel-running, and cocaine preference
(University of Missouri--Columbia, 2024)Estrogen (E2) signaling in the reward circuit of the brain (e.g. nucleus accumbens (NAc)) is known to modulate rewarding behaviors, such as exercise, palatable food intake, and drug use. Women, given constantly fluctuating ... -
Glucose and lipid metabolism : the role of sleep, exercise, and adipose tissue
(University of Missouri--Columbia, 2024)Habitual sleep restriction (SR) (<7 h/night) is widespread in modern society and may be contributing to the development of type 2 diabetes by inducing insulin resistance (IR) in skeletal muscle (SM) and adipose tissue (AT). ... -
The vascular response to hypoxia and sympathetic activation : sex differences and the role of [beta]-adrenergic receptors and nitric oxide
(University of Missouri--Columbia, 2024)[EMBARGOED UNTIL 08/01/2025] During hypoxia, systemic sympathetic vasoconstrictor activity is increased but peripheral vasodilation prevails -- suggesting vasodilatory factors outweigh sympathetically-mediated vasoconstrictor ... -
The effects of 6-weeks of resistance training on the gut microbiome in young adults with overweight and obesity
(University of Missouri--Columbia, 2022)INTRODUCTION: Obesity is a known risk factor for the development of insulin resistance, type 2 diabetes, and other cardiometabolic outcomes. Recently, the gut microbiome had been identified as a possible contributor to the ... -
Changes in blood biomarkers and the microbiome in individuals consuming a high and low fiber diet
(University of Missouri--Columbia, 2022)Dietary fiber is a group of polysaccharides consisting of long chains of various carbohydrate monomers than cannot be digested by the human body (1). High fiber diets are associated with decreases in body mass index, ... -
Role of adropin in arterial stiffening associated with obesity and type 2 diabetes
(University of Missouri--Columbia, 2022)Adropin is a peptide largely secreted by the liver and known to regulate energy homeostasis; however, it also exerts cardiovascular effects. Herein, I tested the hypothesis that low circulating levels of adropin in obesity ... -
Lifestyle treatment in the regression of NASH: insulin resistance, lipid synthesis, and methodological innovation
(University of Missouri--Columbia, 2022)This dissertation is focused on factors that increase risk for nonalcoholic fatty liver disease (NALFD) and the more advanced form nonalcoholic steatohepatitis (NASH). These factors include postprandial lipid handling ... -
The role of heat shock protein 72 in endothelial insulin resistance in type 2 diabetes: using passive heat therapy to improve endothelial insulin responsiveness
(University of Missouri--Columbia, 2022)Impaired endothelial insulin signaling and consequent blunting of insulin-induced vasodilation is a feature of type 2 diabetes (T2D) and contributes to vascular disease and glycemic dysregulation. However, the molecular ... -
Investigating physical activity dispersion throughout recess to maximize activity on the playground: a baseline study
(University of Missouri--Columbia, 2022)Introduction: Obesity is an ongoing epidemic due to a surplus of caloric intake and a lack of physical activity (PA). Longitudinal data suggests that physical inactivity translates from childhood into adulthood. Therefore, ... -
The role of hepatic mitochondrial function and mitochondrial turnover in the development and progression of nonalcoholic fatty liver disease and lifestyle modifications to treat the disease
(University of Missouri--Columbia, 2021)Nonalcoholic fatty liver disease (NAFLD) and its more advanced form steatohepatitis (NASH) is associated with obesity and is an independent risk factor for cardiovascular, liver-related, and all-cause mortality. Available ... -
The influence of menstrual cycle and oral contraceptive pill phases on the vascular response to hypoxia and sympathetic activation in healthy young women
(University of Missouri--Columbia, 2021)INTRODUCTION: Hypoxia elicits peripheral vasodilation to preserve blood flow to metabolically active tissue and is accompanied by an increase in muscle sympathetic nervous system activity (MSNA). Prior data predominantly ... -
The impact of exercise on postural control in patients with Parkinson's disease measured by computerized dynamic posturography
(University of Missouri--Columbia, 2021)Postural instability (PI) is one of the most debilitating symptoms of Parkinson's Disease (PD) that onsets in early stages of disease. The pathophysiology of PI occurs because of complex sensorimotor dysfunction that is ... -
Associations between client choice in food pantries and client food security status
(University of Missouri--Columbia, 2020)This study determined the relationship between client choice and client food security status, and how the relationship was affected by household type. Data was obtained from the Voices for Food Project. Among the various ... -
The role of TRAF3IP2 in obesity-associated vascular insulin resistance and dysfunction
(University of Missouri--Columbia, 2020)[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI-COLUMBIA AT REQUEST OF AUTHOR.] Insulin resistance in the vasculature is a characteristic feature of obesity and contributes to the pathogenesis of vascular dysfunction and ... -
Influence of supervised activity zones during recess on sedentary activity, social skill development, and problem behavior in elementary-aged children
(University of Missouri--Columbia, 2020)[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI--COLUMBIA AT REQUEST OF AUTHOR.] Due to the childhood obesity epidemic, many school-based interventions have been developed to target physical inactivity before it develops ... -
The brown adipose tissue phenoype : metabolic implications
(University of Missouri--Columbia, 2018)[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI SYSTEM AT AUTHOR'S REQUEST.] The prevailing dogma is that thermogenic brown adipose tissue (BAT) contributes to improvements in glucose homeostasis in obesogenic animal ... -
Investigating increased shear stress and physical activity as strategies to improve vascular insulin sensitivity
(University of Missouri--Columbia, 2020)[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Impaired vasodilator actions of insulin in type 2 diabetes (T2D) result in blunted insulin-stimulated skeletal muscle capillary perfusion which limits ... -
Contribution of de novo lipogenesis to the progression of nonalcoholic fatty liver disease
(University of Missouri--Columbia, 2020)This dissertation is focused on understanding the biochemical pathway of de novo lipogenesis (DNL) in humans and how changes in DNL can alter disease states, particularly nonalcoholic fatty liver disease (NAFLD). This ... -
Hormonal regulation of bone health: novel understandings of xenoestrogens and estrogen receptor-[alpha]
(University of Missouri--Columbia, 2020)Estrogen is one of the most influential hormones on bone growth and maintenance throughout the life cycle in both men and women, but there are still unknown roles of estrogen and the estrogen receptors in males. In addition, ... -
The role of hepatocellular eNOS in NAFLD development and hepatic mitochondrial adaptations to exercise
(University of Missouri--Columbia, 2020)Whole body loss of endothelial nitric oxide synthase (eNOS) worsens hepatic mitochondrial function and exacerbates nonalcoholic fatty liver disease/steatohepatitis (NAFLD/NASH) development and progression. However, the ...