Browsing Department of Veterinary Medicine and Surgery (MU) by Thesis Advisor "Giuliano, Elizabeth A."
Now showing items 1-5 of 5
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Detection of Leptospira interrogans in fixed equine eyes affected with end-stage equine recurrent uveitis
(University of Missouri--Columbia, 2007)Equine recurrent uveitis (ERU) is the most frequent cause of blindness in horses worldwide. Leptospira has been implicated as an etiologic agent in some cases of ERU. The objective of this study was to determine the presence ... -
Development of an in-vitro model of equine corneal wound healing : pharmacologic and gene therapy modalities in the reduction of corneal fibrosis
(University of Missouri--Columbia, 2010)Objective: To establish an in vitro model for the investigation of equine corneal wound healing. To accomplish this goal, a protocol to isolate and culture equine corneal keratocytes, fibroblasts and myofibroblasts was ... -
In vitro and ex vivo therapeutic strategies for equine corneal fibrosis
(University of Missouri--Columbia, 2017)[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Purpose: The aims were to (1) To explore the impact of equine corneal fibroblast (ECF) to myofibroblast (ECM) differentiation by altering the expression ... -
Local photodynamic therapy for equine squamous cell carcinoma in a murine model
(University of Missouri--Columbia, 2007)The objectives of the present studies were to evaluate the use of local photodynamic therapy (PDT) on tumor growth inhibition in a murine model of squamous cell carcinoma (SCC). SCC was induced in nude mice by injection ... -
Therapeutic potential of the anti-fibrotic drug Suberanilohydroxamic acid (SAHA) in canine corneal fibrosis
(University of Missouri--Columbia, 2016)Purpose: The aims were to (1) investigate the molecular mechanisms mediating the antifibrotic effect of SAHA in the canine cornea using an in vitro model and (2) to develop a novel in vivo model of corneal fibrosis in dogs ...